Demineralization&amp;ndash;remineralization dynamics in teeth and bone

Neel, Ensanya A. Abou; Aljabo, Anas; Strange, Adam; Ibrahim, Salwa; Coathup, Melanie; Young, Alison; Bozec, Laurent; Mudera, Vivek

doi:10.2147/ijn.s107624

Cited by 465 publications

(257 citation statements)

References 216 publications

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“…Bone is a composite of the inorganic component, carbonate apatite [CO 3 Ap; Ca 10−a (PO 4 ) 6−b (CO 3 ) c ] and the organic components including collagen (Abou Neel et al, ). Interestingly, up to now less attention has been paid to the effect of the carbonate content in an apatitic structure of the commercially available bone substitutes on osteoconductivity or on the replacement of new bone.…”

Section: Introductionmentioning

confidence: 99%

Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation

et al. 2019

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Since bone apatite is a carbonate apatite containing carbonate in an apatitic structure, carbonate content may be one of the factors governing the osteoconductivity of apatitic bone substitutes. The aim of this study was to evaluate the effects of carbonate content on the osteoconductivity of apatitic bone substitutes using three commercially available bone substitutes for the reconstruction of alveolar bone defects of a beagle mandible with simultaneous dental implant installation. NEOBONE, Bio‐Oss, and Cytrans that contain 0.1, 5.5, and 12.0 mass% of carbonate, respectively, were used in this study. The amount of newly formed bone in the upper portion of the alveolar bone defect of the beagle's mandible was 0.7, 6.6, and 39.4% at 4 weeks after surgery and 4.7, 39.5, and 75.2% at 12 weeks after surgery for NEOBONE, Bio‐Oss, and Cytrans, respectively. The results indicate that bone‐to‐implant contact ratio was the largest for Cytrans. Additionally, the continuity of the alveolar ridge was restored in the case of Cytrans, whereas the continuity of the alveolar ridge was not sufficient when using NEOBONE and Bio‐Oss. Both Cytrans and Bio‐Oss that have a relatively larger carbonate content in their apatitic structure was resorbed with time. We concluded that carbonate content is one of important factors governing the osteoconductivity of apatitic bone substitutes.

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Section: Introductionmentioning

confidence: 99%

Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation

et al. 2019

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“…Demineralization is the process caused by inflammation when mineral ions of hydroxyapatite (HA) removed from the hard tissues, particularly in the bone . Even though HA is one of the most stable calcium phosphate salt, the inflammation process might lead to the bone matrix changes following bone loss.…”

Section: Discussionmentioning

confidence: 99%

Early crestal bone loss: Is it really loss?

Puišys¹,

Auzbikaviciute²,

Minkauskaite³

et al. 2019

Clinical Case Reports

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“…According to Neel et al, 2016, Coke may lead to demineralization in all, the outermost surface, subsurface and superficial demineralisation. Erosion begins when the acids in soft drinks encounter the tooth enamel, which is the outermost protective layer on your teeth.…”

Section: Discussionmentioning

confidence: 99%

HMU fluorinze mouthwash enhances enamel remineralization: An in vitro study

Ngọc¹,

Coulton²,

Tra³

et al. 2019

Open Access Maced J Med Sci

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BACKGROUND: Fluoride therapy has long been used extensively to prevent dental caries. Fluoride appears in variety of dental care products such as mouthrinse, dentifrice, gel, etc. HMU fluorinze is the first mouthwash containing fluoride in Vietnam. AIM: This research was conducted to evaluate the efficacy of HMU Fluorinze mouthwash on remineralizing enamel in laboratory conditions. METHODS: 20 third molars teeth were cleaned and covered with nail polish , except for a 3x3 mm square on their buccal surfaces. These teeth went through two steps: demineralization using Coke and remineralization for 20 days: 1) using standard calcifying solution (control group) and 2) using standard calcifying solution + HMU Fluorinze mouthwash 2 times/day (experimental group). The mineralization index of enamel structure after demineralization and remineralization was assessed by DIAGNOdent pen 2190. RESULTS: The mineralization indexes of the control group and experimental group at baseline were 3.65 ± 0.76 and 3.35 ± 0.64, after demineralization were in turn of 21.78 ± 4.48 and 20.25 ± 2.26; and after remineralization were 6.30 ± 1.03 and 3.90 ± 1.24. The different figures between the two groups after remineralization shows statistical significance (p<0.01). Group B using HMU fluorinze mouthwash after 20 days did not differ from the original results (p = 0.272), in contrast with the control group (p<0.01). CONCLUSIONS: HMU fluorinze mouthwash has better mineralization effect than standard calcifying solution.

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Demineralization–remineralization dynamics in teeth and bone

Cited by 465 publications

References 216 publications

Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation

Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation

Early crestal bone loss: Is it really loss?

HMU fluorinze mouthwash enhances enamel remineralization: An in vitro study

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