Dementia Subtypes in China

Zhang, Zhen Xin; Zahner, Gwendolyn E. P.; Román, Gustavo C.; Liu, Jun; Zhao, Hong; Qu, Qiu Ming; Liu, Xie He; Zhang, Xiao Jun; Zhou, Bing; Wu, Cheng Bing; Tang, Mao Ni; Xia, Hong; Li, Hui

doi:10.1001/archneur.62.3.447

Cited by 190 publications

(72 citation statements)

References 15 publications

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“…Adequate comparisons are therefore difficult to make, though estimations can be obtained by examining the prevalence of dementia and CIND individually. In our study, the prevalence of dementia in those aged 80 years and over is similar to that found in previous studies in China [10,11,12,13] and Japan [14,15]. …”

Section: Discussionsupporting

confidence: 91%

Prevalence and Clinical Predictors of Cognitive Impairment in Individuals Aged 80 Years and Older in Rural China

Shi

Zhang²,

Yue³

et al. 2013

Dement Geriatr Cogn Disord

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Aims: The aim of this study was to estimate the prevalence of cognitive impairment (CI) in individuals aged 80 years and over in rural China and to analyze the associated risk factors. Methods: We conducted a two-phase door-to-door survey of a population in rural Ji County (China). The reference population consisted of individuals aged 80 years or older. A total of 723 individuals were interviewed in their homes, and demographic variables and comorbidities were recorded. Diagnoses were divided into the following 3 categories: normal cognitive function, cognitive impairment no dementia (CIND), and dementia. The odds ratio for each risk factor was calculated by logistic regression analysis. Results: The prevalence of CI among individuals aged 80 years and older was 73.2% (47.4% CIND and 25.7% dementia). The risk of CI decreased with a higher level of education and a higher level of social involvement. The risk of CI was higher in females than in males and among people with a history of stroke (p < 0.01). Conclusions: The observed raw prevalence of CI was 73.2%. Female gender and a history of a previous stroke increased the risk of CI, while a higher educational level and engagement in social activities reduced the risk of CI.

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Section: Discussionsupporting

confidence: 91%

Prevalence and Clinical Predictors of Cognitive Impairment in Individuals Aged 80 Years and Older in Rural China

Shi

Zhang²,

Yue³

et al. 2013

Dement Geriatr Cogn Disord

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“…We estimate that 21.3% of the urban population aged 60 years or older have MCI without dementia in the Hebei province, China. These results suggest that the number of individuals with MCI is about 6.3 times higher than that with dementia, based on the previous prevalence estimate of dementia in 3,700 older individuals in China [19]. Reviews report the prevalence of MCI as ranging from 5 to 29% [20,21].…”

Section: Discussionmentioning

confidence: 62%

High Prevalence of Mild Cognitive Impairment in the Elderly: A Community-Based Study in Four Cities of the Hebei Province, China

Xie²,

Song³

et al. 2014

Neuroepidemiology

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Background: Mild cognitive impairment (MCI) has been suggested as a term for a boundary area between normal aging and dementia. This study was designed to determine the prevalence of MCI in the elderly in the Hebei province, China, and explore its related factors. Methods: Participants included 2,601 community-dwelling people aged 60 years or older who resided in the four major cities of the Hebei province. In stage 1 of the study, the Mini-Mental State Examination and the Montreal Cognitive Assessment were administered for screening purposes. In stage 2, the subjects who screened positive were further examined by neurologists. The diagnosis of MCI was made according to Petersen's criteria. Results: The estimated prevalence of MCI was 21.3%. MCI was more prevalent at age 65-69 (28.3%), and its overall rates among men (24.1%) were higher than those of women (19.9%). The higher prevalence of MCI was associated with very old age (≥80 years old; OR = 2.457, 95% CI = 1.471-4.104), male gender (OR = 1.363, 95% CI = 1.097-1.694), low education level (OR = 2.439, 95% CI = 1.623-3.663), and poor economic status (OR = 2.882, 95% CI = 1.949-4.255). Conclusions: Our findings show a high prevalence of MCI in the elderly urban population in the Hebei province. Gender, education level, and economic status may have an important role in the etiology of MCI.

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“…Two Canadian studies did not find differences in dementia prevalence across Canada (Canadian Study of Health and Aging Working Group 1994; Hébert et al 2000;Manfreda 1995) but suggested the existence of regional differences in dementia subtypes. US-studies found regional differences in Alzheimer's disease prevalence (Steenland et al 2009;Laditka et al 2006a;Laditka et al 2008;Laditka et al 2006b), in Puerto Rico dementia prevalence varied between the eight regions (Figueroa et al 2008), in China a north-south gradient as well as a weaker east-west gradient existed (Zhang et al 2005;Zhang et al 2006). Differences in dementia prevalence were also found in Spain and Finland (Russ et al 2012), as well as in the eastern and western part of Germany ).…”

Section: Introductionmentioning

confidence: 99%

Health Among the Elderly in Germany. New Evidence on Disease, Disability and Care Need

Doblhammer¹

2014

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Dementia Subtypes in China

Abstract: Background: Prevalences of Alzheimer disease (AD) and vascular dementia (VaD) in China reportedly differ from those in Western countries. Objective: To estimate prevalence of AD and VaD in 4 regions of China.

Cited by 190 publications

References 15 publications

Prevalence and Clinical Predictors of Cognitive Impairment in Individuals Aged 80 Years and Older in Rural China

Prevalence and Clinical Predictors of Cognitive Impairment in Individuals Aged 80 Years and Older in Rural China

High Prevalence of Mild Cognitive Impairment in the Elderly: A Community-Based Study in Four Cities of the Hebei Province, China

Health Among the Elderly in Germany. New Evidence on Disease, Disability and Care Need

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