Dementia Improvement after Plasma Exchange for Familial Hypercholesterolemia

Abstract

Worldwide dementia related memory issues affect a great number of patients and families. In this case, a “senior moment” was noted at age fifty and issues with memory and mind progressed resulting in early retirement from work. The patient described here was given a diagnosis of “Pre-Alzheimer's disease” and presented for further accurate evaluation, diagnosis, and management. The medical management resulted in an improvement in the patients memory and cognitive ability.

YangXue QingNao Wan and Silibinin Capsules, the Two Chinese Medicines, Attenuate Cognitive Impairment in Aged LDLR (+/-) Golden Syrian Hamsters Involving Protection of Blood Brain Barrier

“…A large part of homozygous FH patients die of myocardial infarction in their teenage years ( Kastelein et al, 2007 ), while heterozygous FH patients suffer from similar diseases in their middle age and at old age ( Yuan et al, 2006 ). Recently, it is reported that aged heterozygous FH patients are more inclined to suffer from dementia compared with control people, which can be attenuated by long-term statin therapy or plasma exchange ( Hyttinen et al, 2010 ; Orehek, 2016 ). However, long-term statin therapy is reported to have side effects, such as rhabdomyolysis, hepatic injury, and renal failure ( Mukhtar and Reckless, 2005 ; Kromer and Moosmann, 2009 ; Kareem et al, 2017 ).…”