Démence et chutes

Strubel, D.; Jacquot, Julien; Milch, Catherine

doi:10.1016/s0168-6054(00)00057-x

Cited by 27 publications

(6 citation statements)

References 46 publications

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“…People with dementia are more prone to falls and fractures due to cognitive and behavioural disorders, visual and motor problems, gait and balance disturbances, malnutrition, and the adverse effects of medication[81]. Thus there may be a higher pick-up rate for osteoporosis amongst this group.…”

Section: Discussionmentioning

confidence: 99%

Dementia and osteoporosis in a geriatric population: Is there a common link?

Downey

Young

Burton

et al. 2017

WJO

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AIMTo determine the existence of a common pathological link between dementia and osteoporosis through reviewing the current evidence base.METHODSThis paper reviews the current literature on osteoporosis and dementia in order to ascertain evidence of a common predisposing aetiology. A literature search of Ovid MED-LINE (1950 to June 2016) was conducted. The keywords “osteoporosis”, “osteoporotic fracture”, “dementia” and “Alzheimer’s disease” (AD) were used to determine the theoretical links with the most significant evidence base behind them. The key links were found to be vitamins D and K, calcium, thyroid disease, statins, alcohol and sex steroids. These subjects were then searched in combination with the previous terms and the resulting papers manually examined. Theoretical, in vitro and in vivo research were all used to inform this review which focuses on the most well developed theoretical common causes for dementia (predominantly Alzheimer’s type) and osteoporosis.RESULTSDementia and osteoporosis are multifaceted disease processes with similar epidemiology and a marked increase in prevalence in elderly populations. The existence of a common link between the two has been suggested despite a lack of clear pathological overlap in our current understanding. Research to date has tended to be fragmented and relatively weak in nature with multiple confounding factors reflecting the difficulties of in vivo experimentation in the population of interest. Despite exploration of various possible mechanisms in search for a link between the two pathologies, this paper found that it is possible that these associations are coincidental due to the nature of the evidence available. One finding in this review is that prior investigation into common aetiologies has found raised amyloid beta peptide levels in osteoporotic bone tissue, with a hypothesis that amyloid beta disorders are systemic disorders resulting in differing tissue manifestations. However, our findings were that the most compelling evidence of a common yet independent aetiology lies in the APOE4 allele, which is a well-established risk for AD but also carries an independent association with fracture risk. The mechanism behind this is thought to be the reduced plasma vitamin K levels in individuals exhibiting the APOE4 allele which may be amplified by the nutritional deficiencies associated with dementia, which are known to include vitamins K and D. The vitamin theory postulates that malnutrition and reduced exposure to sunlight in patients with AD leads to vitamin deficiencies.CONCLUSIONRobust evidence remains to be produced regarding potential links and regarding the exact aetiology of these diseases and remains relevant given the burden of dementia and osteoporosis in our ageing population. Future research into amyloid beta, APOE4 and vitamins K and D as the most promising aetiological links should be welcomed.

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Section: Discussionmentioning

confidence: 99%

Dementia and osteoporosis in a geriatric population: Is there a common link?

Downey

Young

Burton

et al. 2017

WJO

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“…Low illuminance levels can adversely influence visual acuity, affecting confidence in mobility and fine motor activities [135]. As older people (60 years plus) tend to need approximately three times more light to see as well as younger people (20 years), significantly higher levels of artificial illumination are recommended to support independence and safety in kitchens, bathrooms, and other spaces that host activities requiring good balance or visual acuity [136]. Indoor lighting should ideally comprise multiple fixtures per space so that lighting is evenly distributed and unhelpful shadows are minimised.…”

Section: Light For Health Comfort and Independencementioning

confidence: 99%

Environmental Design for People Living with Dementia

Quirke,

Bennett,

Chau

et al. 2023

Encyclopedia

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The term ‘environmental design for dementia’ relates to both the process and outcomes of designing to support or improve cognitive accessibility in physical environments. Environmental design for dementia is evidenced as an effective nonpharmacological intervention for treatment of the symptoms of dementia and is associated with higher levels of independence and wellbeing for people living with a variety of age-related cognitive, physical, and sensory impairments. Evidence-based dementia design principles have been established as a means of supporting both the design and evaluation of environmental design for dementia.

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“…O objetivo do tratamento fisioterapêutico é proporcionar uma maior independência funcional ao paciente, empregando para isso técnicas que visam manter a força, o tônus e a elasticidade muscular, além de exercícios capazes de promover maior destreza e funcionalidade durante a execução da marcha e outras AVDs associadas à vida do idoso. Em conjunto, o uso de órteses pode ser eventualmente indicado, atentando para o fato de que a má utilização desta pode conduzir a quedas suplementares e agravamento das patologias associadas como dores articulares e encurtamento muscular 46 .…”

Section: Fisioterapia E Estratégias De Prevenção De Quedasunclassified

Efeito preventivo da fisioterapia na redução da incidência de quedas em pacientes com Doença de Alzheimer

2019

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Esta revisão tem como meta proporcionar melhor compreensão do efeito preventivo da intervenção fisioterapêutica para minimizar a ocorrência de quedas em pacientes com Doença de Alzheimer. A Doença de Alzheimer é a principal causa de demência entre pessoas idosas, apresentando nos últimos anos um crescimento rápido do número de acometidos devido ao aumento da expectativa de vida. Embora o paciente portador de Alzheimer apresente em sua fase inicial apenas perdas cognitivas e de linguagem, a evolução progressiva da doença é capaz de gerar um aumento no déficit de equilíbrio, distúrbios na marcha e a possibilidades de ocorrência de quedas. Apesar de alguns estudos apresentarem dados que comprovem o beneficio da fisioterapia em diminuir o risco de quedas, não foi possível chegar a uma conclusão efetiva sobre o efeito preventivo de quedas através da aplicação desta modalidade terapêutica. A pequena quantidade de estudos que enfatizem o tratamento fisioterapêutico sobre a DA, assim como, a padronização de um método fisioterapêutico no tratamento desta doença, faz com que seja necessário o desenvolvimento de novos estudos e diferentes estratégias de prevenção de quedas no tratamento deste grupo de pacientes, almejando minimizar danos motores e prolongar a independência desses pacientes.

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Démence et chutes

Cited by 27 publications

References 46 publications

Dementia and osteoporosis in a geriatric population: Is there a common link?

Dementia and osteoporosis in a geriatric population: Is there a common link?

Environmental Design for People Living with Dementia

Efeito preventivo da fisioterapia na redução da incidência de quedas em pacientes com Doença de Alzheimer

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