Delving into Matrix Metalloproteinase-1 (MMP-1) and its Significance in Periodontal Diseases
Prabhu M. Natarajan,
Anuradha Ganesan,
Sudhir R. Varma
et al.
Abstract:Matrix metalloproteinase-1 (MMP-1) plays a pivotal role in the pathogenesis of periodontal diseases, particularly periodontitis, by virtue of its collagenolytic activity targeting collagen type I, the primary component of periodontal tissues. This review abstract elucidates the intricate involvement of MMP-1 in periodontal tissue homeostasis and its dysregulation in disease states. Elevated MMP-1 levels, observed in gingival tissues and crevicular fluid of individuals with periodontitis, correlate with the deg… Show more
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