Delusional Infestation Secondary to the Dopamine Agonist Ropirinole in a Patient With Parkinson's Disease: A Case Report With an Outline of the Biology of Psychosis

Kesserwani, Hassan

doi:10.7759/cureus.12880

Cited by 2 publications

(2 citation statements)

References 20 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Emotional impact included not minding (58%), unpleasant (23%), or terrible (17%), with preserved insight. SP could precede subsequent VH (41%), involving same or different entities Kesserwani, 2021 [ 106 ] d 83 f na No anxiety or MDD MSH (VH + TH) Ants and splinters of wood invading skin, continued vigorous scratching of arms and legs, resulting in excoriation and scabbing. Calm acknowledgement, with minimal distress Kulick et al, 2018 [ 46 ] 67.0 ± 8.0, 54% male, 28 8.5 ± 6.4 Atypical Parkinsonism, or organic psychosis excluded MSH (OH + GH), VH, AH, OH, TH, GH, SP Visions of people (14%) or animals (7%), with voices (4%) or music (7%) reported.…”

Section: Resultsmentioning

confidence: 99%

Non-visual hallucinations in Parkinson’s disease: a systematic review

et al. 2023

View full text Add to dashboard Cite

Background Non-visual hallucinations in Parkinson’s disease (PD) can be prevalent and distressing. Most existing research has however, focused on visual hallucinations as well as related risk factors. The current study thus conducted a systematic review to collate existing evidence on non-visual hallucinations in PD, focusing on their prevalence, phenomenology, and clinical-cognitive correlates. Methods Ninety-one relevant studies were included from a systematic search across PsycINFO APA, PubMed, and Web of Science, for peer-reviewed publications in the English language, from 1970 to the present. These comprised a mix of case (30 studies; n = 56) and group design (62 studies; n = 7346) studies, divided into three somewhat overlapping collections to address our three research foci. Results Prevalence estimates for hallucinations were: auditory 1.5–72.0%, olfactory 1.6–21.0%, somatic-tactile 0.4–22.5%, gustatory 1.0–15.0%, and sensed presence 0.9–73.3%. Phenomenological inquiries revealed descriptions of vivid, consuming events replete with elaborate detail, adversely affecting PD patients in different ways. Overt experiences of multisensory hallucinations were also highly variable (0.4–80%) but exceedingly common, reported by almost half of the 45 included prevalence studies. There was some evidence for modality-specific hallucination predictors, but this was largely tentative, pending robust replication. Conclusions Marked prevalence figures coupled with phenomenological descriptions implicating distress denote that non-visual and multisensory hallucinations in PD are of clinical significance. More direct research and clinical attention need to be devoted to the study and management of such hallucinatory experiences.

show abstract

Section: Resultsmentioning

confidence: 99%

Non-visual hallucinations in Parkinson’s disease: a systematic review

et al. 2023

View full text Add to dashboard Cite

show abstract

“…This mismatch may lead to apathy. The Papez circuit links the hippocampus with the cingulate cortex, and degeneration of the entorhinal cortex by transsynaptic degeneration may involve the cingulate cortex, leading to apathy [8].…”

Section: Introductionmentioning

confidence: 99%

Apathy Antedating and Evolving With Dementia: A Case Report and Insights Into Apathy as a Network Dysfunction

Kesserwani¹

2021

Cureus

Self Cite

View full text Add to dashboard Cite

Apathy is a motivational disorder characterized by a lack of drive or indifference to salient endogenous or exogenous influences or stimuli. In the classical literature, it was referred to as a lack of mental energy or vitality and attributed to dysfunction of the ergotropic sympathetic pathway involving the posterior hypothalamus, thalamus, cingulate cortex, and hippocampal formation. Recent advanced imaging studies have expanded the ambit of network dysfunction to include the dopaminergic mesolimbic system and the salience network that gauges the valence or energy of the mesolimbic system. The classic Papez circuit also has a role in the pathogenesis of apathy. In order to understand the mechanisms of apathy seen with a wide range of diseases including neurodegenerative disorders, trauma, and strokes, one needs to think of apathy as a network disorder. In this report, we present a case of apathy antedating and evolving with Alzheimer's disease and delve into the network theory of apathy and explore potential pharmacological therapies.

show abstract

Delusional Infestation Secondary to the Dopamine Agonist Ropirinole in a Patient With Parkinson's Disease: A Case Report With an Outline of the Biology of Psychosis

Cited by 2 publications

References 20 publications

Non-visual hallucinations in Parkinson’s disease: a systematic review

Non-visual hallucinations in Parkinson’s disease: a systematic review

Apathy Antedating and Evolving With Dementia: A Case Report and Insights Into Apathy as a Network Dysfunction

Contact Info

Product

Resources

About