Delta OD450 and doppler velocimetry of the middle cerebral artery peak velocity in the evaluation for fetal alloimmune hemolytic disease: Which is best?

Fetal Doppler: Umbilical Artery, Middle Cerebral Artery, and Venous System

“…(We also noted that the MCA PSV had an important advantage in that it is noninvasive.) 18 The accuracy of the MCA PSV was confirmed by Pereira and coworkers 19 in a retrospective study-the same approach we used. More recently, a multicenter prospective study has determined that the MCA PSV is actually more reliable than the delta OD 450 in the diagnosis of fetal anemia, 20 which has led the American College of Obstetrics and Gynecology to report that the MCA PSV is an excellent tool for the diagnosis of fetal anemia in the hands of trained people.…”

Middle cerebral artery peak systolic velocity for the diagnosis of fetal anemia: the untold story

“…In 1997, we reported that the MCA‐PSV is superior to amniocentesis in detecting anemia in cases at risk of anemia35. Pereira et al in 2003, confirmed these results36.…”