Delta hepatitis: molecular biology and clinical and epidemiological features.

Polish, L B; Gallagher, M; Fields, H A; Hadler, S C

doi:10.1128/cmr.6.3.211-229.1993

Cited by 8 publications

(13 citation statements)

References 124 publications

(163 reference statements)

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“…Up to 5% of the world's population is infected with hepatitis B virus (HBV), and probably 5% of the HBV carriers have hepatitis D virus (HDV) superinfection [1] . It is estimated that 15 million people are infected with HDV worldwide [2] . Superinfection of HDV in persons with HBV infection leads to progressive disease and cirrhosis in approximately 80% of cases [3] .…”

Section: Introductionmentioning

confidence: 99%

Clinical presentation and genotype of hepatitis delta in Karachi

Moatter

Abbas²,

Shabir³

et al. 2007

WJG

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Section: Introductionmentioning

confidence: 99%

Clinical presentation and genotype of hepatitis delta in Karachi

Moatter

Abbas²,

Shabir³

et al. 2007

WJG

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“…Although the infection resources in the society and contagion types are similar with HBV, the distribution and contamination rates in the world are different. It has been assumed that more than 5% of 300 million hepatitis B virus surface antigen (HBsAg) carriers, approximately 15 million people, are infected with HDV (3). Regarding the HDV endemicity in the population, four broad classifications of HDV infection have been defined: "very low", "low", "middle" and "high endemicity.…”

Section: Introductionmentioning

confidence: 99%

Defining the Delta Virus Positivity in Hepatitis B Virus Infections

Karadağ

Yılmaz²,

Goren³

et al. 2014

vhd

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The aim of this study was to retrospectively analyze the frequency of anti-hepatitis delta virus (anti-HDV) antibody in hepatitis B virus surface antigen (HBsAg)-positive cases. Materials and Methods: Anti-HDV and anti-hepatitis B virus core antigen (anti-HBc) IgM seropositivity was researched using ELISA method in patients who attended the clinical microbiology laboratory at Ondokuz Mayıs University Medical Faculty Hospital between August 2005 and August 2010 and were determined to be positive for HBsAg. Results: A total of 2314 HBsAg-positive patients were included in this study. Anti-HDV positivity was detected in 36 (1.56%) of them. By taking the anti-HBc IgM seropositivity as reference, among patients who had positive delta antibody, 33 (91.67%) subjects were evaluated as "super-infection" and 3 (8.33%) patients were evaluated as "co-infection". Conclusion: Although anti-HDV positivity in our region is relatively lower than in the other regions, emphasis should be given to the prevention and monitoring researches due to the high level of mortality and morbidity of the illness.

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“…The hepatitis delta virus (HDV) is a small, single stranded RNA hepatotropic virus that depends on hepatitis B virus (HBV) for its survival and replication (Polish et al . , 1993;Purcell, 1994; Karayiannis, 1998).…”

Section: Introductionmentioning

confidence: 99%

“…, 1984). In regions where HDV infection is not endemic, the disease is mostly confined to groups at high risk of acquiring HBV infection and high-risk HBV carriers (Polish et al . , 1993).…”

Section: Introductionmentioning

confidence: 99%