Delivery System for Targeted Drug Therapy in Chronic Diseases

Abstract

Chronic diseases affect many people and have become the leading cause of death and loss of health worldwide. The etiology of chronic diseases is complex. They are usually incurable and require continual medical management. Many chronic diseases deteriorate with time, resulting in an enormous burden on society and patients' families. During the past years, targeted agents have made improved the management of various chronic diseases. An optimal drug delivery system can improve the therapeutic efficacy of these targeted drugs and reduce systemic adverse effects, bringing benefits for patients with chronic diseases. Here, we highlight recent research progress in the development of targeted therapeutic drugs for chronic diseases and improved delivery systems.

Regulating Reactive Oxygen Species in Rheumatoid Arthritis: Insights into Cell Signaling Pathways and Nano-Particles as Carriers

“…Regulating Reactive Oxygen Species in Rheumatoid Arthritis: Insights into Cell Signaling… DOI: http://dx.doi.org/10.5772/intechopen.113191 anti-inflammatory medications with nanoparticles can significantly increase therapeutic specificity and efficacy [42]. Nanoparticles can be designed to act passively or actively target inflammatory cells and tissues, resulting in a more focused and effective treatment [80]. The ability to minimize harm to normal cells is one of the key benefits of employing nanoparticles in ROS control therapy for RA [51].…”