Delivery of Indocyanine Green, a Photosensitizer, Into Balloon-Injured Atherosclerotic Plaque of Hyperlipidemic New Zealand Rabbits

Abstract

Introduction: Indocyanine Green (ICG) has been demonstrated to be a potent photosensitizer for photodynamic therapy. Although most of the work on ICG has been focused on its potential applications as photosensitizer in Photodynamic Therapy (PDT) for cancer treatment, ICG may have potential clinical use in the treatment of atherosclerosis, both de novo and in restenosis.