Delivery of gefitinib loaded nanoparticles for effectively inhibiting prostate cancer progression

Abstract

Androgen deprivation therapy is administered to suppress the growth of prostate cancer (PCa). However, some cells continue to proliferate independently of hormones, leading to the development of castration-resistant prostate cancer...

Sorafenib Encapsulated Poly(ester amide) Nanoparticles for Efficient and Biosafe Prostate Cancer Therapy

“…54 According to the research by Xiong et al, the use of gefitinib-loaded poly(D,L-lactide-co-glycolide) acid nanoparticles demonstrated significant effectiveness in preventing the advancement of prostate cancer. 55 In a separate research project, it was discovered that the utilization of poly Lglutamic acid (PGA)-loaded anti-insulin growth factor 1 receptor antibody (known as AVE1642) effectively suppressed the advancement of tumors in an orthotopic prostate cancer mouse model. 56 The drug carrier 8P4 NPs used in this study is an L-phenylalanine polymer with good biocompatibility and biodegradability.…”

“…Shu et al endeavored to attach hyaluronic acid (HA) to a zeolite imidazolate backbone material to conduct MRI imaging of PC-3 cells in human prostate cancer . According to the research by Xiong et al, the use of gefitinib-loaded poly­( d , l -lactide- co -glycolide) acid nanoparticles demonstrated significant effectiveness in preventing the advancement of prostate cancer . In a separate research project, it was discovered that the utilization of poly l -glutamic acid (PGA)-loaded anti-insulin growth factor 1 receptor antibody (known as AVE1642) effectively suppressed the advancement of tumors in an orthotopic prostate cancer mouse model .…”