Delineation of the larynx as organ at risk in radiotherapy: a contouring course within “Rete Oncologica Piemonte-Valle d’Aosta” network to reduce inter- and intraobserver variability

Cante, Domenico; Petrucci, Edoardo; Piva, Cristina; Borca, Valeria Casanova; Sciacero, Piera; Bertodatto, Maurizio; Marta, Caterina; Franco, Pierfrancesco; Viale, M; Valle, Giovanni La; Porta, Maria Rosa La; Bertetto, Oscar

doi:10.1007/s11547-016-0668-8

Cited by 8 publications

(6 citation statements)

References 34 publications

(43 reference statements)

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“…Apart from the introduction of atlas-based auto-contouring programs in the clinical practice, which proved to be beneficial in time reduction compared to the manual contouring [26], the possibility of expanding the role of CSRTs in the pre-planning phase represents a major asset. Several studies have already confirmed the great potential of CSRTs in normal tissue contouring in the head and neck and the pelvic districts [10][11][12][13]27].…”

Section: Discussionmentioning

confidence: 98%

The emerging role of radiation therapists in the contouring of organs at risk in radiotherapy: analysis of inter-observer variability with radiation oncologists for the chest and upper abdomen

Arculeo

Miglietta

Nava

et al. 2020

ecancer

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Aims: To compare the contouring of organs at risk (OAR) between a clinical specialist radiation therapist (CSRT) and radiation oncologists (ROs) with different levels of expertise (senior-SRO, junior-JRO, fellow-FRO). Methods: On ten planning computed tomography (CT) image sets of patients undergoing breast radiotherapy (RT), the observers independently contoured the contralateral breast, heart, left anterior descending artery (LAD), oesophagus, kidney, liver, spinal cord, stomach and trachea. The CSRT was instructed by the JRO e SRO. The inter-observer variability of contoured volumes was measured using the Dice similarity coefficient (DSC) (threshold of ≥ 0.7 for good concordance) and the centre of mass distance (CMD). The analysis of variance (ANOVA) was performed and a p-value < 0.01 was considered statistically significant. Results: Good overlaps (DSC > 0.7) were obtained for all OARs, except for LAD (DSC = 0.34 ± 0.17, mean ± standard deviation) and oesophagus (DSC = 0.66 ± 0.06, mean ± SD). The mean CMD < 1 cm was achieved for all the OARs, but spinal cord (CMD = 1.22 cm). By pairing the observers, mean DSC > 0.7 and mean CMD < 1 cm were achieved in all cases. The best overlaps were seen for the pairs JRO-CSRT(DSC = 0.82; CMD = 0.49 cm) and SRO-JRO (DSC = 0.80; CMD = 0.51 cm). Conclusions: Overall, good concordance was found for all the observers. Despite the short training in contouring, CSRT obtained good concordance with his tutor (JRO). Great variability was seen in contouring the LAD, due to its difficult visualization and identification of CT scans without contrast.

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Section: Discussionmentioning

confidence: 98%

The emerging role of radiation therapists in the contouring of organs at risk in radiotherapy: analysis of inter-observer variability with radiation oncologists for the chest and upper abdomen

Arculeo

Miglietta

Nava

et al. 2020

ecancer

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“…In this article, the mean volume refers to the average volume delineated by the five observers. Conformity index (CI) and Dice coefficient (DC) were used in articles with similar research methods, which can be used to express the consistency of delineation between observations ( 15 ). The mean volume, CI, and DC of each sequence were compared to determine the variability between observers.…”

Section: Methodsmentioning

confidence: 99%

Reduction of inter-observer variability using MRI and CT fusion in delineating of primary tumor for radiotherapy in lung cancer with atelectasis

Zhang

Min

et al. 2022

Front. Oncol.

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PurposeTo compare the difference between magnetic resonance imaging (MRI) and computed tomography (CT) in delineating the target area of lung cancer with atelectasis.MethodA retrospective analysis was performed on 15 patients with lung cancer accompanied by atelectasis. All positioning images were transferred to Eclipse treatment planning systems (TPSs). Six MRI sequences (T1WI, T1WI+C, T1WI+C Delay, T1WI+C 10 minutes, T2WI, DWI) were registered with positioning CT. Five radiation oncologists delineated the tumor boundary to obtain the gross tumor volume (GTV). Conformity index (CI) and dice coefficient (DC) were used to measure differences among observers.ResultsThe differences in delineation mean volumes, CI, and DC among CT and MRIs were significant. Multiple comparisons were made between MRI sequences and CT. Among them, DWI, T2WI, and T1WI+C 10 minutes sequences were statistically significant with CT in mean volumes, DC, and CI. The mean volume of DWI, T2WI, and T1WI+C 10 minutes sequence in the target area is significantly smaller than that on the CT sequence, but the consistency is higher than that of CT sequences.ConclusionsThe recognition of atelectasis by MRI was better than that by CT, which could reduce interobserver variability of primary tumor delineation in lung cancer with atelectasis. Among them, DWI, T2WI, T1WI+C 10 minutes may be a better choice to improve the GTV delineation of lung cancer patients with atelectasis.

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“…Pre-operative RT is a well-established option to provide tumor downsizing and downstaging and to increase loco-regional control in this setting [3] . Selection and delineation of clinical target volume (CTV) and organs at risk (OARs) are crucial steps to deliver precise and tailored radiation [4] , [5] , [6] . While the sites and subsites of irradiation are, to some extent, agreed by physicians, the boundaries of CTVs still remain controversial, leading to inhomogeneous contours and systematic errors with standard deviations as high as 1 cm, as reported in different studies [7] , [8] .…”

Section: Introductionmentioning

confidence: 99%

Variability of clinical target volume delineation for rectal cancer patients planned for neoadjuvant radiotherapy with the aid of the platform Anatom-e

Franco

Arcadipane

Trino

et al. 2018

Clinical and Translational Radiation Oncology

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HighlightsDelineation of treatment volumes is a major source of uncertainties in rectal cancer radiotherapy.Anatom-e is an electronic platform working as an image-based delineation system.The use of Anatom-e was able to decrease the inter-observer variability in the delineation process of clinical target volumes for locally advanced rectal cancer.Anatom-e may be potentially helpful in increasing the compliance to common guidelines and protocols.

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Delineation of the larynx as organ at risk in radiotherapy: a contouring course within “Rete Oncologica Piemonte-Valle d’Aosta” network to reduce inter- and intraobserver variability

Cited by 8 publications

References 34 publications

The emerging role of radiation therapists in the contouring of organs at risk in radiotherapy: analysis of inter-observer variability with radiation oncologists for the chest and upper abdomen

The emerging role of radiation therapists in the contouring of organs at risk in radiotherapy: analysis of inter-observer variability with radiation oncologists for the chest and upper abdomen

Reduction of inter-observer variability using MRI and CT fusion in delineating of primary tumor for radiotherapy in lung cancer with atelectasis

Variability of clinical target volume delineation for rectal cancer patients planned for neoadjuvant radiotherapy with the aid of the platform Anatom-e

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