Delineation of Human Carotid Plaque Features &lt;italic&gt;In Vivo&lt;/italic&gt; by Exploiting Displacement Variance

Torres, Gabriela; Czernuszewicz, Tomasz J.; Homeister, Jonathon W.; Caughey, Melissa C.; Huang, Benjamin; Lee, Ellie R.; Zamora, Carlos; Farber, Mark A.; Marston, William A.; Huang, David; Nichols, Timothy C.; Gallippi, Caterina M.

doi:10.1109/tuffc.2019.2898628

Cited by 21 publications

(1 citation statement)

References 42 publications

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“…More interestingly, this parameter was also used in the study to classify specific components within the plaque, including thin fibrous caps, lipid-rich necrotic cores, and intraplaque hemorrhages ( 88 ). In addition, Torres et al combine signal correlation and signal-to-noise ratio (SNR), expressed as a decimal logarithm of the acceleration variance, either directly or through displacement variance, called “log(Vo A)” to successfully describe the composition and structure of human carotid atherosclerotic plaque ( 89 ). Overall, these results are all clinically useful for predicting stroke risk and facilitating medical management.…”

Section: Elastographymentioning

confidence: 99%

Novel ultrasound techniques in the identification of vulnerable plaques—an updated review of the literature

Yao

Zhang

2023

Front. Cardiovasc. Med.

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Atherosclerosis is an inflammatory disease partly mediated by lipoproteins. The rupture of vulnerable atherosclerotic plaques and thrombosis are major contributors to the development of acute cardiovascular events. Despite various advances in the treatment of atherosclerosis, there has been no satisfaction in the prevention and assessment of atherosclerotic vascular disease. The identification and classification of vulnerable plaques at an early stage as well as research of new treatments remain a challenge and the ultimate goal in the management of atherosclerosis and cardiovascular disease. The specific morphological features of vulnerable plaques, including intraplaque hemorrhage, large lipid necrotic cores, thin fibrous caps, inflammation, and neovascularisation, make it possible to identify and characterize plaques with a variety of invasive and non-invasive imaging techniques. Notably, the development of novel ultrasound techniques has introduced the traditional assessment of plaque echogenicity and luminal stenosis to a deeper assessment of plaque composition and the molecular field. This review will discuss the advantages and limitations of five currently available ultrasound imaging modalities for assessing plaque vulnerability, based on the biological characteristics of the vulnerable plaque, and their value in terms of clinical diagnosis, prognosis, and treatment efficacy assessment.

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Section: Elastographymentioning

confidence: 99%