Delineation of Choroidal and Retinal Lesions in Posterior Uveitis by Multispectral Wide-Field Scanning Laser Ophthalmoscopy

Knickelbein, Jared E.; Hasan, Jesia; Nussenblatt, Robert B.; Sen, H. Nida

doi:10.1097/iae.0000000000001050

Cited by 14 publications

(5 citation statements)

References 12 publications

(12 reference statements)

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“…lwBAF (488 nm excitation wavelength) can be used as an imaging tool to monitor patients in terms of disease progression during treatment [41]. Some data suggest that a larger number of choroidal lesions can be identified using a laser with 635 nm excitation wavelength compared to 532 nm [42]. Interestingly, macular hyperfluorescent lesions are not associated with worse LogMAR visual acuity [43].…”

Section: Serpiginous Choroiditis (Sc)mentioning

confidence: 99%

Fundus Autofluorescence in Posterior and Panuveitis—An Under-Estimated Imaging Technique: A Review and Case Series

Mauschitz,

Zeller,

Sagar

et al. 2024

Biomolecules

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Fundus autofluorescence (FAF) is a prompt and non-invasive imaging modality helpful in detecting pathological abnormalities within the retina and the choroid. This narrative review and case series provides an overview on the current application of FAF in posterior and panuveitis. The literature was reviewed for articles on lesion characteristics on FAF of specific posterior and panuveitis entities as well as benefits and limitations of FAF for diagnosing and monitoring disease. FAF characteristics are described for non-infectious and infectious uveitis forms as well as masquerade syndromes. Dependent on the uveitis entity, FAF is of diagnostic value in detecting disease and following the clinical course. Currently available FAF modalities which differ in excitation wavelengths can provide different pathological insights depending on disease entity and activity. Further studies on the comparison of FAF modalities and their individual value for uveitis diagnosis and monitoring are warranted.

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Section: Serpiginous Choroiditis (Sc)mentioning

confidence: 99%

Fundus Autofluorescence in Posterior and Panuveitis—An Under-Estimated Imaging Technique: A Review and Case Series

Mauschitz,

Zeller,

Sagar

et al. 2024

Biomolecules

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“…Similarly, Knickelbein et al . [ 68 ] demonstrated that a higher percentage of patients with birdshot choroidopathy had lesions seen on 635 nm imaging than 532 nm as this is primarily a choroidal inflammatory disorder.…”

Section: Ultra-wide Field Imagingmentioning

confidence: 99%

Ultra-wide field retinal imaging

Kumar

Surve

Kumawat

et al. 2021

Indian Journal of Ophthalmology

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The peripheral retina is affected in a variety of retinal disorders. Traditional fundus cameras capture only a part of the fundus even when montaging techniques are used. Ultra-wide field imaging enables us to delve into the retinal periphery in greater detail. It not only facilitates assessing color images of the fundus, but also fluorescein angiography, indocyanine green angiography, fundus autofluorescence, and red and green free images. In this review, a literature search using the keywords “ultra-widefield imaging”, “widefield imaging”, and “peripheral retinal imaging” in English and non-English languages was done and the relevant articles were included. Ultra-wide field imaging has made new observations in the normal population as well as in eyes with retinal disorders including vascular diseases, degenerative diseases, uveitis, age-related macular degeneration, retinal and choroidal tumors and hereditary retinal dystrophies. This review aims to describe the utility of ultra-wide field imaging in various retinal disorders.

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“…Birdshot chorioretinopathy (BCR), which has also been referred to as vitiliginous chorioretinitis, is an inflammatory posterior uveitic syndrome characterized by deep small-to-medium-sized round or oval hypopigmented choroidal lesions radiating from the optic nerve in a pattern similar to birdshot from a shotgun ( Figure 1 ) [ 3 , 4 ]. Birdshot lesions are easily detected by the 635 nm laser on Optos ® imaging as perivascular choroidal lesions ( Figure 1 ) [ 5 ]. ICGA shows characteristic hypofluorescent choroidal spots that correspond to and are typically greater in number than the clinically apparent lesions during active disease ( Figure 2 ) [ 6 ].…”

Section: Birdshot Chorioretinopathymentioning

confidence: 99%

Multimodal Imaging of the White Dot Syndromes and Related Diseases

Knickelbein¹,

Sen²

2016

J Clin Exp Ophthalmol

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The white dot syndromes encompass a group of rare posterior uveitis conditions that are characterized by outer retinal and/or choroidal hypopigmented lesions that are thought to be inflammatory in nature. The size, shape, and location of lesions in the fundus aid in differentiating these conditions. Multimodal imaging, including modalities such as fundus autofluorescence, optical coherence tomography, fluorescein angiography, and indocyanine green angiography, among others, has become integral in diagnosing and monitoring many of the white dot syndromes. Furthermore, multimodal imaging modalities have provided insights into the pathogenesis and exact sites within the retina and choroid affected by white dot syndromes.

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Delineation of Choroidal and Retinal Lesions in Posterior Uveitis by Multispectral Wide-Field Scanning Laser Ophthalmoscopy

Abstract: Retinal and choroidal lesions in patients with posterior uveitis can be differentially visualized with Optos 532 nm and 635 nm lasers, respectively, allowing determination of depth of pathology.

Cited by 14 publications

References 12 publications

Fundus Autofluorescence in Posterior and Panuveitis—An Under-Estimated Imaging Technique: A Review and Case Series

Fundus Autofluorescence in Posterior and Panuveitis—An Under-Estimated Imaging Technique: A Review and Case Series

Ultra-wide field retinal imaging

Multimodal Imaging of the White Dot Syndromes and Related Diseases

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