Deliberate self-poisoning in an Irish county hospital

McMahon, Graham T.; McGarry, Kathleen

doi:10.1007/bf03168817

Cited by 13 publications

(7 citation statements)

References 33 publications

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“…Our data do not agree with some recent findings indicating NSAIDs (particularly paracetamol) as drugs frequently used for parasuicidal purposes [4,6,18]. …”

Section: Discussioncontrasting

confidence: 99%

Untitled

Mauri

Cerveri

Volonteri

et al. 2005

Clin Pract Epidemiol Ment Health

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Epidemiological knowledge of parasuicides and drug self-poisoning is still limited by a lack of data. A number of preliminary studies, which require further analysis, evidenced that parasuicidal acts occur more often among females, that the peak rate is generally recorded between the ages of 15 and 34 years and psychotropic medications seems to be the most frequently used. The aim of this study was to describe the demographic and clinical variables of a sample of subjects admitted to the Posisoning Treatment Centre (CAV), Niguarda General Hospital, Milan, following drug self-poisoning. Furthermore, this study is aimed to identify the risk factors associated to parasuicidal gestures, with special care for the used drugs, the presence of psychiatric or organic disorders, alcoholism and drug addiction.The study included the 201 patients attending the CAV in 1999 and 2000 who satisfied the criteria of self-poisoning attempts: 106 cases in 1999 and 95 in 2000.The sample had a prevalence of females (64%). The peak rates of parasuicides from drug self-poisoning were reached between 21 and 30 years among the females, and 31 and 40 years among the males. 81.6% of the patients used one or more psychoactive drugs, the most frequent being the benzodiazepines (58.7%), classic neuroleptics (16.9%) and new-generation antidepressants (SSRIs, SNRIs, NARIs) (12.9%). The prevalence of mood disorders was higher among females (64% vs 42%), whereas schizophrenia was more frequently diagnosed in males (22% vs 10%). 61% (33%) had a history of previous attempted suicides. The presence of clinically relevant organic diseases was observed in 24.9% of the sample.

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“…Our data do not agree with some recent findings indicating NSAIDs (particularly paracetamol) as drugs frequently used for parasuicidal purposes [4,6,18]. …”

Section: Discussioncontrasting

confidence: 99%

Untitled

Mauri

Cerveri

Volonteri

et al. 2005

Clin Pract Epidemiol Ment Health

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“…It was reported that 50% of adult poisonings were with 2-3 agents by Mc Mahon et al (22). Fifty three percent of poisonings with drugs were with analgesics, 31% with multiple drugs (vitamin, antihistamines, antibiotics, digestive system drug, antitussive) and 16% with psychiatric drugs (tricyclic antidepressants, SSRIs).…”

Section: Discussionmentioning

confidence: 99%

A retrospective analysis of acute poisoning during pregnancy

Karadaş¹,

Güler²,

Aydın³

2011

J Turkish German Gynecol Assoc

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Objective:The aim of this study is to investigate and analyse pregnant women who were admitted to our emergency service due to acute poisoning. Material and Methods:All cases were retrospectively collected from our computer records and emergency record book between 01. 01.2006 and 01.01.2010; the registration data on age, gravidity, gestational week, whether the poisoning was deliberate or accidental, causative agent, admission time, treatment results and mortality outcome were collected and analyzed.Results: Eighty eight women admitted with acute poisoning were known to be pregnant and the poisoning was accidental in 23% of the cases, while 77% were suicidal intoxications. 74% of patients were in the 21-34 age group. Accidental intoxications were due to carbon monoxide, foods and cleaning products. 75.4% of the suicidal poisonings were caused by medical drugs, with analgesics, multiple drugs and psychiatric drugs being the top culprits and accounted for 53%, 31% and 16% of drug poisonings respectively. In terms of gestational week, 47.4% of suicidal poisonings were within the first trimester and the relationship between suicidal attempt and gestational week was found to be statistically significant (p<0.015). However, the relationship between gravidity and the rate of suicidal attempts was not statistically significant (p=0.214). All patients were followed up and treated in the emergency service and no mortality was observed in the study. Bulgular: Acil servise akut zehirlenme ile ba vuran 88 gebe olgunun %77'si özk y m amaçl , %23'ü kazara olu an zehirlenmeler idi. Olgular n %74'ü 21-34 ya grubundayd . Kazara olan zehirlenmeler karbon monoksit, besin ve temizlik ürünlerine ba l yd . Özk y m amaçl zehirlenmelerin %75.4'ünde etken medikal ilaçlar olup s ras yla %53 analjezikler, %31 çoklu ilaçlar ve %16 oran nda da psikiyatrik ilaçlar saptand . Gebelik haftas na göre, özk y m amaçl zehirlenmelerin %47.4'ü 1. trimesterda olup gebelik haftas ile özk y m giri imi aras ndaki ili ki istatistiksel olarak anlaml bulundu (p<0.015). Ancak, gravida ile öz-k y ma te ebbüs etme aras ndaki ili ki istatistiksel olarak anlaml bulunmad (p=0.214). Olgular n tamam n n takip ve tedavisi acil serviste yap ld , çal mada ölüm vakas na rastlanmad . Conclusion:Sonuç: Gebelikteki akut zehirlenme vakalar n n ço u özk y m amaç-l d r. Gebeler özk y ma en fazla gebeli in ilk üç ay nda te ebbüs etmektedir. ntihar amac yla en s k kullan lan madde ise t bbi ilaçlard r. (J Turkish-German Gynecol Assoc 2011; 12: 199-203)

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“…A review of 16 studies that included data on acute alcohol use and suicide attempts found that on average, 40% of attempters had used alcohol, with some estimates ranging as high as 73%, similar rates of alcohol use were found among completed suicides (Cherpitel et al, 2004). Three studies directly measuring blood alcohol level (Borges and Rosovsky, 1996; McMahon and McGarry, 2001; Suokas and Lonnqvist, 1995) found a significant association between suicide attempts and recent alcohol consumption. There is some evidence for a dose–response relationship whereby the more alcohol consumed, the greater the risk of suicidal behavior (Borges and Rosovsky, 1996).…”

Section: Discussionmentioning

confidence: 99%

Effect of acute alcohol use on the lethality of suicide attempts in patients with mood disorders

Sher¹,

Oquendo²,

Richardson-Vejlgaard³

et al. 2009

Journal of Psychiatric Research

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Acute alcohol use is an important risk factor for attempted and completed suicide. We evaluated the effect of acute alcohol intake on the lethality of suicide attempts to test the hypothesis that acute alcohol intoxication is associated with more lethal suicide attempts. This retrospective study included 317 suicide attempters enrolled in mood disorders protocols. Demographic and clinical parameters were assessed. The use of alcohol at the time of the most lethal suicide attempt was determined. On the basis of their responses participants were classified into three groups: participants who reported “Enough alcohol intake to impair judgment, reality testing and diminish responsibility” or “Intentional intake of alcohol in order to facilitate implementation of attempt” were included in the group “Alcohol” (A); participants who reported “Some alcohol intake prior to but not related to attempt, reportedly not enough to impair judgment, reality testing” were included in the group “Some Alcohol” (SA); and participants who reported “No alcohol intake immediately prior to attempt” were included in the group “No Alcohol” (NA). Lethality of the most lethal suicide attempts was higher in the A group compared to the SA and NA groups. Prevalence of patients with alcohol use disorders was higher in the A group compared to the SA and NA groups. SA participants reported more reasons for living and lower suicide intent scores at the time of their most lethal suicide attempt compared to the A and NA groups. Acute alcohol use increases the lethality of suicide attempts in individuals with mood disorders.

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Deliberate self-poisoning in an Irish county hospital

Abstract: Deliberate self-poisoning remains a significant problem. Paracetamol and alcohol use are particularly marked in this population. The combination of tricyclic antidepressant drugs and alcohol were the most dangerous.

Cited by 13 publications

References 33 publications

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A retrospective analysis of acute poisoning during pregnancy

Effect of acute alcohol use on the lethality of suicide attempts in patients with mood disorders

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