We present a general quantum deletion algorithm that deletes M marked states from an N-item quantum database with arbitrary initial distribution. The general behavior of this algorithm is analyzed, and analytic result is given. When the number of marked states is no more than 3N 4 , this algorithm requires just a single query, and this achieves exponential speedup over classical algorithm. [6][7][8][9][10], recent interests have been focused on quantum algorithms using duality mode in a quantum register [11,12]. Deleting an item from a database is a routine task in database processing. In classical computing, deleting operation is an essential method to preserve data structure for convenient searching and visiting. For instance, in the basis technique of well-known Google search engine -PageRank algorithm [13,14], the most frequently clicked N items are selected from the magnanimity of information. Then the first N nodes form a heap structure and web pages with respect to the marked nodes are deleted to preserve the first N nodes Deleting items in a database is a widely met scientific problem in quantum computing. Some certain items do not satisfy the computing demands, then one should delete them. We have proposed quantum deletion algorithm [17] that deletes a marked item from unsorted N = 2 n item database. However, in a variety of practical cases, it would be desirable to apply it to deleting multiple number of marked items and non-uniform initial distribution, where N is not essentially the power of 2. This could arise in situations where the deletion is used as a subroutine in a large quantum computation. Another example would be the given that initial distribution is intrinsically non-uniform and the marked solution is not unique.In this article, we generalize a quantum deletion algorithm [17] to the case that the number of marked items is more than one, the initial amplitudes are complex and follow an arbitrary distribution. Moreover we analyze the general behavior of deletion operator and give analytic results. Finally, we