Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment

Zachariae, H

doi:10.1111/j.1365-2133.1988.tb02574.x

Cited by 156 publications

(109 citation statements)

References 8 publications

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“…1,2 Prior to isotretinoin initiation, patients are often warned of the possible risk of abnormal scarring following such procedures, and this risk is also mentioned in the patient information leaflet for isotretinoin supplied by the manufacturers. 3 Whether the risk of abnormal scarring extends to other forms of elective or emergency surgery is less clear.…”

Section: Introductionmentioning

confidence: 99%

Should isotretinoin be stopped prior to surgery? A Critically Appraised Topic

Wootton

Cartwright²,

Manning

et al. 2014

Br J Dermatol

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Section: Introductionmentioning

confidence: 99%

Should isotretinoin be stopped prior to surgery? A Critically Appraised Topic

Wootton

Cartwright²,

Manning

et al. 2014

Br J Dermatol

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“…Although a controversial topic, oral isotretinoin intake within 6 months of ablative, aggressive resurfacing techniques, such as dermabrasion, may lead to a higher risk of delayed wound healing and keloidal scarring [9][10][11]. It is unclear, however, whether the same contraindication applies to nonablative technologies, as there have been no published reports of such a complication following these less aggressive procedures.…”

Section: Patient Selection and Pre-procedural Carementioning

confidence: 83%

Non‐Ablative Resurfacing

Berlin

Goldberg

2010

Facial Resurfacing

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“…We believe that the possible causes may be summarized as follows: (1) nutritionally deprived states, such as starvation, acute or chronic illness and dietary fads increase the risk of deficiency of ascorbic acid essential for normal collagen synthesis as a required co-factor for the hydroxylation of proline and lysine [17]; (2) hypervitaminosis A in AN may produce similar effects to those reported in patients treated with isotretinoin in whom delayed healing after dermabrasion and laser surgery has been described [18]. …”

Section: Discussionmentioning

confidence: 99%

Skin Signs in Anorexia nervosa

et al. 2001

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Background: Eating disorders are becoming an epidemic in Europe, particularly among young women, but European studies concerning this topic are few. In eating disorders, significant medical complications occur in all of the primary human organ systems, including the skin. Objective: The purpose of this study was to improve the knowledge of skin signs in anorexia nervosa (AN) and verify whether cutaneous differences exist between the restrictive type and the bulimic type. Methods: A noncontrolled clinical study was performed in 24 consecutive patients with the restrictive and the bulimic types of AN in order to verify whether the cutaneous signs are different in the two types. The dermatological examination included the entire skin, oral cavity, hair and nails, with attention to skin pathologies prior to the development of AN. Results: In all the patients, the most frequent skin manifestations were xerosis (58.3%), hair effluvium (50%), nail changes (45.8%), cheilitis (41.6%), acne (41.6%), gingivitis (33.3%), acrocyanosis (29%), diffuse hypertrichosis (25%), carotenoderma (20.8%), generalized pruritus (16.6%), hyperpigmentation (12.5%), striae distensae (12.5%), factitial dermatitis, seborrheic dermatitis (8.3%), poor wound healing, melasma and Russell’s sign (4.1%). In the patients with the bulimic type of AN, hair effluvium, acne, gingivitis, nail changes and generalized pruritus were more frequent than in the patients with the restrictive type. Russell’s sign and seborrheic dermatitis were exclusively detected in the bulimic type. Hyperpigmentation, striae distensae, factitial dermatitis, poor wound healing and melasma were exclusively observed in the restrictive type. Cheilitis, diffuse hypertrichosis and carotenoderma were more represented in the restrictive type. Two patients with restrictive type of AN were followed up for a period of 3 years. In both, xerosis, cheilitis, acrocyanosis, hyperpigmentation and acne improved in relation to the increase in BMI. Hair effluvium and diffuse hypertrichosis appeared not to be linked to this parameter. Conclusion: Skin changes are prevalent among patients with AN. Some changes seem to depend on the type of AN or to be linked to the BMI.

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Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment

Abstract: We report the observation of delayed wound healing and keloid formation in three patients, following dermabrasion or Argon laser treatment administered while they were receiving isotretinoin for acne or rosacea.

Cited by 156 publications

References 8 publications

Should isotretinoin be stopped prior to surgery? A Critically Appraised Topic

Should isotretinoin be stopped prior to surgery? A Critically Appraised Topic

Non‐Ablative Resurfacing

Skin Signs in Anorexia nervosa

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