Delayed wound healing after tooth extraction and self-reported kyphosis in Japanese men and women

Abstract

It is unclear whether osteoporosis itself is a main risk factor for delayed wound healing after tooth extraction in humans. In this study, we evaluated the association between experience of delayed wound healing after last tooth extraction and self-reported kyphosis, with the possibility of having vertebral fractures, in Japanese patients. Among the 1,504 patients who responded to the structured questionnaire survey, 518 patients (134 men and 384 women) aged 55–97 years finally participated in this study. Patients who self-reported mild-moderate kyphosis were more likely to have problematic delayed wound healing after last tooth extraction than those who reported severe kyphosis (odds ratio [OR] 4.98; 95% confidence interval [CI], 1.86–13.38 and OR 2.30; 95% CI, 0.52–10.22, respectively) (p for trend = 0.005). Japanese patients with vertebral fractures may have a higher risk of having problematic delayed wound healing after tooth extraction.

Antiresorptive agent-related osteonecrosis of the jaw in osteoporosis patients from Asian countries

“…In a recent study designed to elucidate the association between osteoporosis and delayed wound healing after tooth extraction, self-reported kyphosis was used as a surrogate marker for spine fractures, owing to its significant association with spine fractures [21] . In this study, which included 518 subjects (134 men and 384 women) aged 55–97 years, those who self-reported mild-moderate kyphosis were significantly more likely to have delayed wound healing after tooth extraction as compared with those who reported no kyphosis (odds ratio [OR], 4.98; 95% CI, 1.86–13.38) [22] .…”