Delayed Menopause Due to Ovarian Granulosa Cell Tumour

Vyas, M; Manjeera, Lakshmi; Rai, Supriya

doi:10.7860/jcdr/2013/6911.3507

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…Juvenile type was histologically distinguished from adult type by the lack of Call-Exner bodies which small punched out spaces lined by granulosa cells giving a follicle-like appearance. Adult type accounts 95% of all GCTO and juvenile type approximately 5% (Vyas et al, 2013). In our study, juvenile type GCTO was detected in only one woman (3%).…”

Section: Discussioncontrasting

confidence: 42%

Parameters for Predicting Granulosa Cell Tumor of the Ovary: A Single Center Retrospective Comparative Study

Yeşilyurt¹,

Tokmak²,

Güzel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: To evaluate factors for predicting the granulosa cell tumor of the ovary (GCTO) pre-operatively. Materials and Methods: This retrospective designed study was conducted on 34 women with GCTO as the study group and 76 women with benign ovarian cysts as the control group. Data were recorded from the hospital database and included age, body mass index (BMI), parity, serum estradiol (E 2 ) levels, diameter of the mass, ultrasonographic features, serum CA125 level, risk of malignancy index (RMI), duration of menopause, postoperative histopathology result, and the neutrophil/lymphocyte ratio (NLR). Results: The demographic parameters showed no statistically significant difference between the groups. Preoperative diameter of the mass, CA125, duration of menopause, and neutrophil/lymphocyte ratio were significantly different between the groups. ROC curve analysis demonstrated that diameter of the mass, serum estradiol and Ca125 levels, RMI and NLR may be discriminative factors in predicting GCTO preoperatively. Conclusions: In conclusion, we think that a careful preoperative workshop including diameter of the mass, serum estradiol (E 2 ) and Ca125 levels, RMI and NLR may predict GCTO and may prevent incomplete approaches.

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Section: Discussioncontrasting

confidence: 42%

Parameters for Predicting Granulosa Cell Tumor of the Ovary: A Single Center Retrospective Comparative Study

Yeşilyurt¹,

Tokmak²,

Güzel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…One of rare symptom or way of presentation of GCTs could be delayed menopause. 4 Other signs and symptoms are similar to most ovarian malignancies. Ascites is present in 10% of cases and rarely a pleural effusion is present as seen in our case.…”

Section: Physical Findingsmentioning

confidence: 89%

A case of postmenopausal bleeding with an unusual finding

Rudra

Thakur

2020

Int J Reprod Contracept Obstet Gynecol

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Authors report the case of a 55-year-old patient who presented with postmenopausal bleeding. On clinical evaluation uterus was 12 weeks size with a left sided adnexal cystic mass of 8 × 6 cm size. Further imaging studies revealed uterus size of 11.5 × 6.7 × 6.3 cm, left ovarian mass of size 8.4 × 6.7 × 6 cm and endometrial thickness of 17 mm on ultrasonography. She underwent endometrial biopsy to exclude endometrial cancer. The report of which came to be endometrial hyperplasia without atypia. Further MRI study confirmed the findings of USG of a complex cystic lesion of left adnexa 75 × 57 × 60 mm. Tumor marker for ovarian tumors were sent and inhibin B was found to be markedly raised. A provisional diagnosis of GCT (Granulosa cell tumour) was made and staging laparotomy was done. The uterus was found to be 12 × 8 cm size and a left sided ovarian cyst of 8-9 cm size with smooth wall and intact capsule was found. Patient had an uneventful postoperative recovery.

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“…This tumor produces estrogen, reason for EH, recurrence uterine bleeding, and early diagnosis. About 70% of tumors are hormone secreting [12]. The most common presentation in premenopausal and menopausal age group is abnormal uterine bleeding (53.7%).…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Ovarian Fibrothecoma in a Premenopausal Women with Recurrent Menorrhagia

Rexhepi

Trajkovska

Ismaili

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: Ovarian fibrothecoma is a rare, benign, sex cord-stromal neoplasm, with a typically unilateral location in the ovary, characterized by mixed features of both fibroma and thecoma. Ovarian fibrothecoma is uncommon tumor of gonadal stromal cell origin accounting for 3-4% of all ovarian tumours. CASE PRESENTATION: We presented a rare case of a 46-year-old patient with recurrent menorrhagia in the past two years with no previous medical, surgical or gynecological history. She underwent two times curettage procedures. At the admission to hospital ultrasonography showed a homogenous solid right ovarian mass of size 2.5 cm x 3.5 cm. Endometrial curettage revealed simple hyperplasia of the endometrium. Diagnostic evaluation and surgical management are discussed along with a brief review of the literature. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was carried out. Histopathology confirmed fibrothecoma of the ovary, proliferative endometrium with hyperplasia without atypia and multiple uterine fibroids. CONCLUSION: In all patients presenting with recurrent menorrhagia and adnexal tumor the possibility of a granulosa cell tumor must be kept in mind during evaluation.

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Delayed Menopause Due to Ovarian Granulosa Cell Tumour

Cited by 3 publications

References 6 publications

Parameters for Predicting Granulosa Cell Tumor of the Ovary: A Single Center Retrospective Comparative Study

Parameters for Predicting Granulosa Cell Tumor of the Ovary: A Single Center Retrospective Comparative Study

A case of postmenopausal bleeding with an unusual finding

A Case Report of Ovarian Fibrothecoma in a Premenopausal Women with Recurrent Menorrhagia

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