Delayed hypersensitivity reaction from microneedling twenty years after silicone fillers

Ahn, Grace S.; Ting, Michelle; Liu, Catherine Y.; Korn, Bobby S.; Kikkawa, Don O.

doi:10.1080/01676830.2022.2037141

Cited by 2 publications

(1 citation statement)

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“…In comparison, other skin rejuvenation treatments like laser therapy and IPL provide deeper skin rejuvenation and address more significant issues such as deep wrinkles and texture concerns with longer-lasting results, albeit with potentially more downtime and a higher risk of side effects. Treatments like microneedling and dermal fillers offer benefits beyond the reach of AHAs by adding substantial volume and reducing deep wrinkles, 118 , 119 while Botox and other neurotoxins target muscle contractions to smooth out wrinkles, 120 particularly in the upper face. Thus, while AHAs offer excellent superficial rejuvenation suitable for a broad range of skin types, more invasive treatments may be necessary for more pronounced signs of aging or specific skin conditions.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the Efficacy and Safety of Alpha-Hydroxy Acids in Dermatological Practice: A Comprehensive Clinical and Legal Review

Almeman

2024

CCID

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The global market for alpha-hydroxy acids (AHAs) is undergoing significant expansion, propelled by increasing demand for skincare products that address aging and environmental damage. This review focuses on the dermatological applications of AHAs, particularly in cosmetic formulations like chemical peels. We have identified that AHAs, such as glycolic and lactic acids, enhance skin rejuvenation by promoting apoptosis in skin cells, boosting collagen and elastin synthesis, and improving skin texture and luminosity. Our comprehensive analysis reveals a nuanced understanding of AHAs’ effectiveness across various skin types and conditions, demonstrating their broad utility in treating conditions like acne, hyperpigmentation, and photoaging. However, the optimal concentrations for therapeutic efficacy with minimal side effects are yet to be precisely defined, necessitating further research. Regulatory compliance is underscored as essential for the safe application of AHAs in cosmetics, with international guidelines recommending specific concentrations and pH levels to minimize potential skin irritation. In Conclusion, the review highlights the effectiveness of AHAs in cosmetic dermatology, emphasizing the necessity for continued research and rigorous regulatory adherence to maximize their safe and beneficial application worldwide.

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Section: Discussionmentioning

confidence: 99%