Delayed haemolytic transfusion reaction due to Kidd antibodies

Joyisa, Deb; Kaur, Daljit; Suhasini, Sil; Davood, Bava; Aswin, Mohan K; Jain, Ashish; Negi, Gita

doi:10.1016/j.tracli.2022.03.001

Cited by 1 publication

(1 citation statement)

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“…We present this case of a blood type O LT recipient who presented with a rare combination of anti-D and anti-Jk(a) antibodies, necessitating coordination with the blood bank and supplier to obtain timely dual antigen-negative RBCs for transfusion to prevent potential HTRs in a high-risk patient. 2,3 As transplantation in patients with liver failure is associated with anticipated risks of bleeding due to impaired coagulation, significant perioperative hemostatic and RBC support was anticipated. This infrequently described clinical challenge of Kidd blood system antibodies in a Rhesus −ve patient is the basis for this report and may be of interest to anesthesiologists.…”

Section: Discussionmentioning

confidence: 99%

Blood Management in a Liver Transplant Recipient with Kidd (Jka) and Rhesus (D) Antibodies: A Case Report

Butler,

Hundley,

Lin

et al. 2024

A&A Practice

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A 67-year-old man presented for urgent liver transplantation (LT). Screening revealed the rare combination of antiRhesus (D) and antiKidd Jk(a) antibodies, requiring antigen-negative red blood cells (RBC) for both phenotypes. This combination has not been reported during LT. Compatible RBCs were initially limited, requiring continued communication between the blood bank/blood supplier to obtain more, including frozen, units. Additional strategies included the use of cell salvage and intentional management of coagulopathy to limit bleeding and RBC requirement. This case highlights blood management during LT when D and Jk(a) antibodies may limit RBC supply and emphasizes the need for effective communication with the blood bank.

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Section: Discussionmentioning

confidence: 99%