Delayed Gastric Emptying After Multivisceral Resection for Retroperitoneal Sarcoma

Delayed gastric emptying after aggressive surgery for retroperitoneal sarcoma – Incidence, characteristics, and risk factors

“…In this case series, patients with primary and secondary DGE accounted approximately half and half, while DGE secondary to other complications was more often observed in patients with clinical DGE (30/54, 55.6%) than in those with mild DGE (5/15, 33.3%). A similar trend was also observed in other studies, in which the proportion of patients with secondary clinical DGE reached 64.3% (18/28) after surgery for RPS (29) and 84.1% (37/44) after pancreatic surgery (23). Accordingly, abdominal infection, POPF, and abdominal bleeding (23,24,29) were the most common concurrent complications associated with clinically relevant DGE in the current study.…”

“…A similar trend was also observed in other studies, in which the proportion of patients with secondary clinical DGE reached 64.3% (18/28) after surgery for RPS (29) and 84.1% (37/44) after pancreatic surgery (23). Accordingly, abdominal infection, POPF, and abdominal bleeding (23,24,29) were the most common concurrent complications associated with clinically relevant DGE in the current study.…”

“…Therefore, when reporting major complications of surgery for RPS, DGE is often overlooked, even in high-volume centers, such as the Transatlantic Australasian RPS Working Group (35,36), resulting in a lack of data on the incidence and severity of DGE after surgery for RPS. Based on the widely accepted definition and grading standards proposed by the ISGPS, the incidence of DGE was 28.9% (69/239) and that of clinically relevant DGE was 22.6% (54/239); the rates were slightly lower than those reported by Baia et al (42% and 28%, respectively) (29). In this case series, patients with primary and secondary DGE accounted approximately half and half, while DGE secondary to other complications was more often observed in patients with clinical DGE (30/54, 55.6%) than in those with mild DGE (5/15, 33.3%).…”

“…Postoperative DGE was first described by Warshaw et al (34). Considering the rarity and complexity of surgery for RPS, only one study has specifically reported DGE after MVR for RPS in the English literature to date (29). The current study, which included 239 patients, is potentially the largest single-center case series thus far.…”

“…However, the incidence and characteristics of and risk factors for DGE after surgery for RPS remain unclear. To the extent known, only one study has explicitly reported the incidence and severity of DGE after MVR for RPS (29); in that study, all 100 patients had primary RPS. As one of the largest specialized sarcoma centers in China, we established a treatment algorithm and performed aggressive surgery in patients with primary and recurrent RPS.…”