“…19,20 Gastric acid secretion was assessed in only three studies, [20][21][22] which included the measurement of fasting gastrin and ⁄ or gastric secretion studies after pentagastrin stimulation 20 or the measurement of gastric pH by a consumable radiotelemetric device. 21,22 As regards the type of intervention, in three studies, 18,19,21 the absorption of the drug was investigated before and after eradication treatment in all patients, in one study 20 the effect of eradication therapy on drug absorption was evaluated only in a subset of patients 22 and in two studies, 20,22 the absorption of the drug was investigated with respect to gastric acidity. Thus, in the selected studies, the study design addressed only in part the mechanisms of oral drug absorption.…”