Dehydration‐Toughing Dual‐Solvent Gels with Viscoelastic Transition for Infectious Wound Treatment
Liangyu Wang,
Kuilong Liu,
Shuai Cui
et al.
Abstract:The modulus of traditional biomedical hydrogels increases exponentially meditated by dehydration‐stiffing mechanism, which leads to the failure of interface matching between hydrogels and soft tissue wounds. It is found in our study that the dual‐solvent gels exhibit dehydration‐toughening mechanism with the slowly increasing modulus that are always match the soft tissue wounds. Therefore, dual‐solvent glycerol hydrogels (GCFen‐gly DGHs) were prepared with hydrophobically modified catechol chitosan (hmCSC) and… Show more
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