DegS protease regulates antioxidant capacity and adaptability to oxidative stress environment in Vibrio cholerae
Kaiying Wang,
Huifang Lu,
Mei Zou
et al.
Abstract:Adaptation to oxidative stress is critical for survival of Vibrio cholerae in aquatic ecosystems and hosts. DegS activates the σE envelope stress response. We have previously revealed that DegS may be involved in regulating the oxidative stress response. In this study, we demonstrated that deletion of the degS gene attenuates the antioxidant capacity of V. cholerae. In addition, our results further revealed that the regulation of antioxidant capacity by DegS in V. cholerae could involve the cAMP-CRP complex, w… Show more
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