Degradation of Tuberculoproteins by Incubation With Lysosomal Components of the Mouse Spleen

Degradation of Tuberculoproteins by Cathepsin D-Type Proteinase of Alveolar and Peritoneal Macrophages of Mice

“…Our preceding two papers Kanai and Kondo, 1972) described separation of tuberculin-active peptides from infected mouse lung homogenate and degradation of tuberculoproteins by incubation with the spleen lysosomal component of mice. To connect these observations more closely to the problem of host-parasite relationship in tuberculous infection, an attempt was made to examine to what extent mouse macrophages are capable of degrading tuberculoproteins.…”