Degradation of Contrast Sensitivity Function Following Posterior Vitreous Detachment

Garcia, Giancarlo A.; Khoshnevis, Matin; Yee, Kenneth M.P.; Nguyen-Cuu, Jeannie; Nguyen, Justin H.; Sebag, J.

doi:10.1016/j.ajo.2016.09.005

Cited by 56 publications

(37 citation statements)

References 24 publications

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“…In fact, it has been documented using contrast sensitivity function, that patients with a PVD have a significant reduction in contrast sensitivity function. 97 Laser treatments and pharmacotherapies have been proposed to decrease these symptoms; however, such therapies currently lack sufficient evidence to support their use. 98 Pars plana vitrectomy has been used for removal of floaters, and improvement in contrast sensitivity function has been documented.…”

Section: I++mentioning

confidence: 99%

Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration Preferred Practice Pattern®

et al. 2020

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Section: I++mentioning

confidence: 99%

Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration Preferred Practice Pattern®

et al. 2020

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“…Color fundus photograph represents an imaging diagnostic technique that can determine just how much floaters affect a patient's visual acuity and may have the potential to be used as an objective metric for vitreous floaters. Some reports have been tried to work toward finding some sort of objective metric to quantify and appreciate the degree of visual impairment that patients are experiencing [3,6,14]. Aberrometry can demonstrate the impact of coma that is induced by floaters, particularly when they move into the central visual axis.…”

Section: Discussionmentioning

confidence: 99%

“…International Journal of Retina and Vitreous accept the floaters perception without annoyance. Nonetheless, some patients such as pseudophakes and myopes may consider their symptoms disturbing [3,4].…”

Section: Open Accessmentioning

confidence: 99%

“…Vitreous floaters become more frequent in elderly people because of the degenerative vitreous changes that develop throughout life. They are common and usually harmless symptoms without any need for treatment [3]. The natural history of floaters is unpredictable with most of them resolving spontaneously and some worsening visual quality [3].…”

Section: Introductionmentioning

confidence: 99%

“…They are common and usually harmless symptoms without any need for treatment [3]. The natural history of floaters is unpredictable with most of them resolving spontaneously and some worsening visual quality [3]. Although vitreous floaters represent a common symptom in patients, the majority of them…”

Section: Introductionmentioning

confidence: 99%

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Objective assessment of YAG laser vitreolysis in patients with symptomatic vitreous floaters

et al. 2020

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Background: To objectively evaluate YAG laser vitreolysis for symptomatic vitreous floaters using color photo imaging. Methods: In this interventional and prospective study, 32 eyes of 32 patients with symptomatic vitreous floaters secondary to posterior vitreous detachment (PVD) were treated with a single session of yttrium aluminum garnet (YAG) laser. Primary outcomes were objective and subjective changes measured by masked grading of color fundus photographs and National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25), respectively. Secondary outcomes included Early Treatment Diabetic Retinopathy Study (ETDRS), best-corrected visual acuity (BCVA) and adverse events. Wilcoxon signed-rank test was used to analyze the results of the objective and subjective assessments at each time point. P < 0.05 was considered statistically significant. Results: Thirty-two patients (32 eyes; 13 men and 19 women) with symptomatic vitreous floaters were enrolled in this study (mean age: 59.4 years). All study patients were followed up for 6 months. Following the laser vitreolysis, there was a statistically significant improvement in both the near visual function (z = − 2.97; p = 0.003; r = 0.633) and visual disturbance rate (z = − 3.97; p < 0.001; r = 0.84). Distance visual function did not show statistically significant difference after the laser procedure (p = 1.00). Color fundus photograph did reveal vitreous opacity improvement over time in 93.7% of study eyes (partial improvement in 37.5% and total improvement in 56.2% of study eyes). During the follow-up period, recurrence of vitreous floaters, BCVA deterioration and adverse events were not observed. Conclusions: YAG laser vitreolysis decreased the amount of vitreous floaters opacities seen on color fundus imaging and improved related symptoms according to the NEI VFQ-25 responses.

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YAG Laser Vitreolysis vs Sham YAG Vitreolysis for Symptomatic Vitreous Floaters

Shah

Heier

2017

JAMA Ophthalmol

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IMPORTANCE Vitreous floaters are common and can worsen visual quality. YAG vitreolysis is an untested treatment for floaters. OBJECTIVE To evaluate YAG laser vitreolysis vs sham vitreolysis for symptomatic Weiss ring floaters from posterior vitreous detachment. DESIGN, SETTING, AND PARTICIPANTS This single-center, masked, sham-controlled randomized clinical trial was performed from March 25, 2015, to August 3, 2016, in 52 eyes of 52 patients (36 cases and 16 controls) treated at a private ophthalmology practice. INTERVENTIONS Patients were randomly assigned to YAG laser vitreolysis or sham YAG (control). MAIN OUTCOMES AND MEASURES Primary 6-month outcomes were subjective change measured from 0% to 100% using a 10-point visual disturbance score, a 5-level qualitative scale, and National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25). Secondary outcomes included objective change assessed by masked grading of color fundus photography and Early Treatment Diabetic Retinopathy Study best-corrected visual acuity.RESULTS Fifty-two patients (52 eyes; 17 men and 35 women; 51 white and 1 Asian) with symptomatic Weiss rings were enrolled in the study (mean [SD] age, 61.4 [8.0] years for the YAG laser group and 61.1 [6.6] years for the sham group). The YAG laser group reported greater symptomatic improvement (54%) than controls (9%) (difference, 45%; 95% CI, 25%-64%; P < .001). In the YAG laser group, the 10-point visual disturbance score improved by 3.2 vs 0.1 in the sham group (difference, −3.0; 95% CI, −4.3 to −1.7; P < .001). A total of 19 patients (53%) in the YAG laser group reported significantly or completely improved symptoms vs 0 individuals in the sham group (

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Degradation of Contrast Sensitivity Function Following Posterior Vitreous Detachment

Cited by 56 publications

References 24 publications

Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration Preferred Practice Pattern®

Posterior Vitreous Detachment, Retinal Breaks, and Lattice Degeneration Preferred Practice Pattern®

Objective assessment of YAG laser vitreolysis in patients with symptomatic vitreous floaters

YAG Laser Vitreolysis vs Sham YAG Vitreolysis for Symptomatic Vitreous Floaters

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