Degradation of 17α-methyltestosterone by hydroxyapatite catalyst

Savaris, Daniela Langaro; Matos, Roberto de; Lindino, Cléber Antônio

doi:10.4136/ambi-agua.2103

Cited by 7 publications

(4 citation statements)

References 13 publications

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“…Despite all these outstanding characteristics displayed by Oreochromis niloticus, there is still high level of apathy in commercial production of Nile Tilapia due to its precocious maturity and uncontrolled reproduction, resulting in increasing competition for feed, space and oxygen which is followed by stunted growth and low commercial value [19,20,15]. Due to excessive spawning of Tilapia in ponds that results to overpopulation and consequently drop in water quality, several methods have been developed to control reproduction for cost effective production of Nile Tilapia and one of such methods is the use of hormones to masculinize all female tilapia [21,22].…”

Section: Figurementioning

confidence: 99%

“…Androgenic anabolic steroid hormone such as 17 α -methyl testosterone is a derivative of testosterone which potentially increases sexual development in males [27]. 17 α -methyl testosterone (MT) is a synthetic product, a methyl derivative of testosterone used in medicine to suppress testosterone deficiency and treat symptoms of andropause in men [21]. Methyl testosterone treatment of Tilapia fry is the most simple and reliable way to produce all male tilapia stocks, which consistently grow to a large and more uniform size than mixed tilapia [24].…”

Section: Use Of Synthetic Hormones/ Steroidmentioning

confidence: 99%

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Use of Dietary Phytochemicals as control for Excessive Breeding in Nile Tilapia (Oreochromis niloticus): A review

Wokeh¹,

Orose²

2021

GSC Biol. and Pharm. Sci.

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Human population has continued to increase unabatedly with its attendant demands on food in order to ease the difficulties of malnutrition and starvation. This continuous rise in population has clearly indicated that the conventional forms of livestock production and captured fisheries will not be sufficient to solve the problem of high protein demands. Aquaculture remains the best option that can bridge the wide gap between human protein demands and domestic production through the culture of fish species like Nile Tilapia (Oreochromis niloticus). Oreochromis niloticus is one of the most cultured finfish, due to its acceptability as food, fast growth, availability for farmers, ability to breed in captivity, resistance to diseases and harsh environmental conditions. Despite all these outstanding characteristics, there is still high level of apathy in commercial production of Nile Tilapia, due to its precocious maturity and uncontrolled breeding, which results in overpopulation of ponds, stunted growth and low commercial value. To mitigate this challenge, the use of synthetic hormones such as 17α-methyl testosterone has been developed to masculinize female tilapia present in a pond, thereby allowing the production of marketable sized fish since the male grows faster than the female. Though, the use of synthetic hormones has helped in some ways, but the negative effects have necessitated farmers to seek alternatives that are environmental friendly and safe for consumers. Dietary phytochemicals have been established to be good alternatives and their use is now gaining global acceptance. Dietary phytochemicals are bioactive compounds commonly found in plant-based diets such as fruits, vegetables, grains and teas. Dietary phytochemicals when administered to newly hatched tilapia species, influences the undifferentiated gonadal tissue of generic females to develop testicular tissue, thus functioning reproductively as males. Some of these phytochemicals such as Flavonoids, Saponins, Phenolics and Alkaloids are found in plants like Carica papaya seeds, Azadirachta indica, and Mucuna pruriens. The usefulness of these phytochemicals is based on their ability to influence sex reversal in Oreochromis niloticus, cost effect, easily accessible especially by small scale fish farmers, simple to apply, and being safe for both human and the environment since they are more biodegradable than synthetic hormones.

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Section: Figurementioning

confidence: 99%

Section: Use Of Synthetic Hormones/ Steroidmentioning

confidence: 99%

Use of Dietary Phytochemicals as control for Excessive Breeding in Nile Tilapia (Oreochromis niloticus): A review

Wokeh¹,

Orose²

2021

GSC Biol. and Pharm. Sci.

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“…As amostras do efluente na saída dos protótipos foram analisadas medindo-se a absorvância na região espectral do UV-visível entre 200 e 1100 nm, com resolução de ±1 nm no espectrofotômetro Shimadzu PC-1800 duplo feixe, para avaliar a presença de MT e de matéria orgânica, considerando-se que, de acordo com Savaris et al (2018), o hormônio MT apresenta o máximo de absorvância no comprimento de onda de 249 nm.…”

Section: Procedimento Experimental Etapa Processo Bateladaunclassified

Investigação de wetlands construídos empregando resíduo de filtro de cervejaria na retenção do hormônio 17α-metiltestosterona

Castanha

Buffon

Alberton

et al. 2020

G. Sci.

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O lançamento de efluentes da piscicultura contendo o hormônio sintético 17α-metiltestosterona, amplamente empregado na masculinização dos alevinos, evidencia a necessidade de adequar técnicas de tratamento de efluentes para sua remoção ou imobilização na mitigação de possíveis impactos ambientais. Com o intuito de investigar um tratamento adequado e acessível para o efluente contendo o hormônio 17α-metiltestosterona, assim como utilizar material alternativo descartado de processos industriais, foram montados quatro protótipos de wetlands construídos contendo como substrato areia de filtro de piscina ou o resíduo de filtro de cervejaria terra diatomácea, realizando-se análises de UV/VIS, pH, condutividade elétrica, turbidez, DBO5 e DQO, verificando o desenvolvimento vegetal, retenção do hormônio, hidrodinâmica do sistema, a caracterização do resíduo de terra diatomácea e análises de MEV e EDS de amostra da terra diatomácea in natura e a granulometria da areia, sendo empregados dois tipos de processos de tratamento: batelada e em fluxo contínuo. O sistema contendo o resíduo terra diatomácea favoreceu o desenvolvimento vegetal e todos os parâmetros aferidos ficaram de acordo com a legislação vigente e não houve presença detectada do hormônio a jusante do sistema proposto.

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“…This result points to the careful selection of substances Article used in the extraction process of 17α-methyltestosterone in different matrices to avoid agents that may interfere with the analytical signal. However, considering possible 17α-methyltestosterone degradation processes in the environment, several studies in the literature indicate that there is no formation of ketones that could interfere with the analytical signal obtained by the proposed method [33][34][35][36].…”

Section: Articlementioning

confidence: 99%

Development of a Spectrophotometric Method for the Determination of 17α-methyltestosterone

Lindino¹,

Savaris²,

Alberton³

et al. 2019

Br J Anal Chem

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Contamination of waters by 17α-methyltestosterone (MT) has increased in recent years due to the increase in the fish farms production. This work describes the determination of the MT hormone by a new spectrophotometric method in the visible region, after the reaction with potassium nitroprusside with the generation of a compound having maximum absorbance at 400 nm. To understand the process of the compound formation, geometry optimizations were performed at MPW1PW91/6-311+G (2d,2p) level of theory and the calculations showing that the NO group of nitroprusside bonds to the carbon with double bond adjacent to the carbonyl of 17α-methyltestosterone. In this method, MT was determined at the concentration between 8.0 x 10 -8 and 2.7 x 10 -7 mol L -1 with a coefficient of determination of 0.9946. The relative standard deviation for the repeatability in nine replicates was 2.37% for [MT] = 1.50 x 10 -7 mol L -1 . Limit of detection (LOD) was calculated as 1.75 x 10 -8 mol L -1 and the limit of quantification (LOQ) was established as the lowest value of the linear concentration range (8.0 x 10 -8 mol L -1 ). This spectrophotometric method was suitable according to the analysis of analytical figures of merit, it has low cost and can be applied to samples of fish farm waters with portable spectrophotometers for in situ measurements, increasing the environmental control with rapid analysis.

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Degradation of 17α-methyltestosterone by hydroxyapatite catalyst

Cited by 7 publications

References 13 publications

Use of Dietary Phytochemicals as control for Excessive Breeding in Nile Tilapia (Oreochromis niloticus): A review

Use of Dietary Phytochemicals as control for Excessive Breeding in Nile Tilapia (Oreochromis niloticus): A review

Investigação de wetlands construídos empregando resíduo de filtro de cervejaria na retenção do hormônio 17α-metiltestosterona

Development of a Spectrophotometric Method for the Determination of 17α-methyltestosterone

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