Degradation and toxicity of bisphenol A and S during cold atmospheric pressure plasma treatment

Kovačić, Ana; Modić, Martina; Hojnik, Nataša; Štampar, Martina; Gulin, Martin Rafael; Nannou, Christina; Koronaiou, Lelouda-Athanasia; Heath, David; Walsh, James L.; Žegura, Bojana; Lambropoulou, Dimitra A.; Cvelbar, Uroš; Heath, Ester

doi:10.1016/j.jhazmat.2023.131478

Cited by 9 publications

(1 citation statement)

References 48 publications

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“…This study adds crucial knowledge to the field of food safety, particularly in using gas plasma technology for toxin degradation. Previous studies have demonstrated the potential of plasma technology in inactivating various pathogens and toxins [ 42 , 43 ]. For example, a review article written by Kutasi et al [ 44 ] highlighted the challenges and approaches towards inactivating aflatoxins using UV radiation and pulsed light treatment, ammoniation, ozonation, and gas plasma.…”

Section: Discussionmentioning

confidence: 99%

Degradation of Toxins Derived from Foodborne Pathogens by Atmospheric-Pressure Dielectric-Barrier Discharge

Sakudo,

Yagyu

2024

IJMS

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Foodborne diseases can be attributed not only to contamination with bacterial or fungal pathogens but also their associated toxins. Thus, to maintain food safety, innovative decontamination techniques for toxins are required. We previously demonstrated that an atmospheric-pressure dielectric-barrier discharge (APDBD) plasma generated by a roller conveyer plasma device is effective at inactivating bacteria and fungi in foods. Here, we have further examined whether the roller conveyer plasma device can be used to degrade toxins produced by foodborne bacterial pathogens, including aflatoxin, Shiga toxins (Stx1 and Stx2), enterotoxin B and cereulide. Each toxin was spotted onto an aluminum plate, allowed to dry, and then treated with APDBD plasma applied by the roller conveyer plasma device for different time periods. Assessments were conducted using a competitive enzyme-linked immunosorbent assay (ELISA) and liquid chromatography–tandem mass spectrometry (LC-MS/MS). The results demonstrate a significant time-dependent decrease in the levels of these toxins. ELISA showed that aflatoxin B1 concentrations were reduced from 308.6 µg/mL to 74.4 µg/mL within 1 min. For Shiga toxins, Stx1 decreased from 913.8 µg/mL to 65.1 µg/mL, and Stx2 from 2309.0 µg/mL to 187.6 µg/mL within the same time frame (1 min). Enterotoxin B levels dropped from 62.67 µg/mL to 1.74 µg/mL at 15 min, and 1.43 µg/mL at 30 min, but did not display a significant decrease within 5 min. LC-MS/MS analysis verified that cereulide was reduced to below the detection limit following 30 min of APDBD plasma treatment. Taken together, these findings highlight that a range of foodborne toxins can be degraded by a relatively short exposure to plasma generated by an APDBD using a roller conveyer device. This technology offers promising advancements in food safety, providing a novel method to alleviate toxin contamination in the food processing industry.

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Section: Discussionmentioning

confidence: 99%