Degradable polycaprolactone nanoparticles stabilized via supramolecular host–guest interactions with pH-responsive polymer-pillar[5]arene conjugates

Abstract

Smart nano-carriers such as micelles, vesicles or nanoparticles constructed from amphiphilic polymers promise a new generation of drug delivery systems featuring localized and controlled release.

Precision polymer nanofibers with a responsive polyelectrolyte corona designed as a modular, functionalizable nanomedicine platform

“…DLS has been used previously by Schubert et al to assess the degradation of PCL-based nanoparticles by following the count rate, which indicates the number of remaining particles. 127 We therefore exposed 137 nm P1 nanofibers ( Đ = 1.05, σ = 30 nm) and 14 nm P1 nanospheres ( Đ = 1.05, σ = 3 nm) to TLL with activity levels of >1 000 000 U L −1 at 37 °C in 5mM NaCl, following the evolution of the D h value and count rate (Fig. 7).…”

Synthesis of a novel aminobenzene-containing hemicucurbituril and its fluorescence spectral properties with ions

“…Macrocycles with converging binding sites and functional groups hold a key position in supramolecular chemistry, which has been repeatedly confirmed by classic macrocyclic molecules, such as crown ethers, cyclodextrins, calixarenes, cucurbiturils and their homologues [1]. For the past decades, numerous intriguing macrocycles have come into our sight, cycloparaphenylenes [2][3][4][5][6][7][8], pillararenes [9][10][11][12], tiaraarenes [13,14], coronaarenes [15][16][17], heteracalixaromatics [18,19], and hemicucurbiturils [20] for instance, and these modified macrocycles have been applied into practical domains, such as chemosensors [21], drug delivery [22], and nano materials preparation [23].…”