Degenerative lumbar spinal stenosis and lumbar spine configuration

Abbas, Janan; Hamoud, Kamal; May, Hila; Hay, Ori; Medlej, Bahaa; Masharawi, Youssef; Peled, Nathan; Hershkovitz, Israel

doi:10.1007/s00586-010-1516-5

Cited by 43 publications

(56 citation statements)

References 77 publications

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“…Among the various problems with spinal aging, lumbar spinal stenosis (LSS) is the most frequent indication for spinal surgery in people over 60 years old 5. LSS refers to narrowing of the spinal canal, nerve root canals, or intervertebral foramina of the lumbar spine 6.…”

Section: Introductionmentioning

confidence: 99%

Changes in Spinal Canal Diameter and Vertebral Body Height with Age

et al. 2013

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PurposeAll structures of the spine, including the spinal canal, change continuously with age. The purpose of this study was to determine how the spinal canal of the lumbar spine changes with age. The L4/5 is the most common site of spinal stenosis and has the largest flexion-extension motion, whereas the T5/6 has the least motion. Therefore, we measured the spinal canal diameter and vertebral body height at T5, T6, L4, and L5 with age.Materials and MethodsThis was a retrospective study of aged 40 to 77 years. We reviewed whole spine sagittal MRIs of 370 patients with lumbar spinal stenosis (LSS) (Group 2) and 166 herniated cervical disc (HCD) (Group 1). Each group was divided into four age groups, and demographic parameters (age, gender, height, weight, BMI), the mid-spinal canal diameter, and mid-vertebrae height at T5, T6, L4, L5 were compared. Within- and between-group comparisons were made to evaluate changes by age and correlations were carried out to evaluate the relationships between all parameters.ResultsHeight, weight, and all radiologic parameters were significantly lower in Group 2 than Group 1. Group 1 did not show any differences, when based on age, but in Group 2, height, weight, and T6, L4, and L5 height were significantly decreased in patients in their 70's than patients in their 40's, except for spinal canal diameter. Age was associated with all parameters except spinal canal diameter.ConclusionVertebral height decreased with age, but spinal canal diameter did not change in patients with either LSS or HCD. Mid-spinal canal diameter was not affected by aging.

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Section: Introductionmentioning

confidence: 99%

Changes in Spinal Canal Diameter and Vertebral Body Height with Age

et al. 2013

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“…Intermittent claudication caused by neuropathic pain (NP) is a special chief complaint of LSS, which may be reconstructed by clinical workers; however, its mechanisms remain unclear. It is now commonly accepted that NP is associated with coccygeal nerve regional pathology, regional blood flow, neuroelectrical physiological changes, and varied compression on the nerves or spinal cord (6)(7)(8)(9)(10). Dorsal root ganglia (DRG) are the primary neurons of afferent pain perception that synthesize diverse control factors, and are a key relay station linking the peripheral and central nervous systems.…”

Section: Introductionmentioning

confidence: 99%

Brain-derived neurotrophic factor expression in dorsal root ganglia of a lumbar spinal stenosis model in rats

Liu

Chu

et al. 2013

Molecular Medicine Reports

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Abstract. This study aimed to investigate the expression of brain-derived neurotrophic factor (BDNF) in dorsal root ganglia (DRG) of a rat model of lumbar spinal stenosis (LSS). Adult male rats were divided into the operation and sham operation groups. The operation group was comprised of the rat models of LSS. Walking distance and BDNF expression levels in DRG were measured in the two groups at different time points. The total BDNF protein levels and positive cell mean optical density (MOD) values in the operation group were significantly higher at each time point compared with that of the sham operation and preoperative control groups (P<0.05). The total BDNF protein levels and MOD values following sport in the operation group were significantly higher compared with those prior to sport (P<0.05). In the sham operation group, BDNF protein levels and MOD values before and after sport at each time point showed no significant differences than those of the operation group (P>0.05). Moreover, BDNF protein levels and MOD values in the operation group indicated a negative correlation with walking distance. The present study demonstrated that the expression of BDNF in rat models of LSS increased with time and was associated with a decrease in walking distance. BDNF was therefore important for the process of intermittent claudication caused by LSS.

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“…Yagi analyzed 120 patients with degenerative LSS, and found there was causal relationship between paravertebral muscle and global spine alignment 15. Abbas studied 167 individuals with or without the symptoms of degenerative LSS, found lumbar lordosis and sacral slope were significantly smaller in the individuals with symptoms than those without 16. Moreover, some studies have confirmed the effect of CSE on paravertebral muscles 17.…”

Section: Discussionmentioning

confidence: 98%

Does the effectiveness of core stability exercises correlate with the severity of spinal stenosis in patients with lumbar spinal stenosis?

Chen

Lin

Zhang³

et al. 2017

Pak J Med Sci

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Objective:To determine whether the effectiveness of core stability exercises correlates with the severity of spinal stenosis in patients with degenerative lumbar spinal stenosis.Methods:Forty-two patients with degenerative lumbar spinal stenosis treated in the department of orthopedics of our hospital between May 2013 and January 2016 were included in the study. All the patients performed core stability exercises once daily for six weeks, and the clinical outcomes were evaluated using Japanese Orthopaedic Association (JOA) score and self-reported walking capacity. The anteroposterior osseous spinal canal diameter was measured to evaluate the severity of spinal stenosis. The correlation between the stenosis degree and the differences of Japanese Orthopaedic Association score or self-reported walking capacity at baseline and after treatment were analyzed.Results:The patients were divided into three groups according to the spinal stenosis degree. In the three groups, there was no significant difference in JOA or self-reported walking distance at baseline (p>0.05) and after treatment (p>0.05). The JOA scores and self-reported walking distance were significantly increased after treatment (p<0.05) in any of the three groups when compared to the baseline. Also, there was no significant correlation between the stenosis degree and the difference of JOA (p>0.05) or self-reported walking distance (p>0.05).Conclusion:There was no significantcorrelation between the effectiveness of core stability exercises and the severity of spinal stenosis in patients with degenerative lumbar spinal stenosis.

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Degenerative lumbar spinal stenosis and lumbar spine configuration

Cited by 43 publications

References 77 publications

Changes in Spinal Canal Diameter and Vertebral Body Height with Age

Changes in Spinal Canal Diameter and Vertebral Body Height with Age

Brain-derived neurotrophic factor expression in dorsal root ganglia of a lumbar spinal stenosis model in rats

Does the effectiveness of core stability exercises correlate with the severity of spinal stenosis in patients with lumbar spinal stenosis?

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