Degenerative joint disease in captive waterfowl

Degernes, Laurel A.; Lynch, P. S.; Shivaprasad, H. L.

doi:10.1080/03079457.2010.541421

Cited by 17 publications

(16 citation statements)

References 54 publications

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“…Synovium fibrosis is a characteristic lesion of chronic cases as that reported by Davis et al [41] and Eldin & Ibrahim [43]. Some forms of grossly observed injuries are demonstrated in Figure1 are almost parallel to those obtained by Degernes et al [5] and Hassan et al [4]. Meanwhile, our microscopical results are in harmony with those recorded by some authors [49,5,4,47,48].…”

Section: Discussionsupporting

confidence: 90%

“…Some forms of grossly observed injuries are demonstrated in Figure1 are almost parallel to those obtained by Degernes et al [5] and Hassan et al [4]. Meanwhile, our microscopical results are in harmony with those recorded by some authors [49,5,4,47,48]. The obtained results of heterophilic and /or lymphocytic infiltration of the synovial membrane, synovial fold, and tendon collagen in most of the arthritic cases depends on the type of infection whatever bacterial or viral one consequently which supported by the results of previously mentioned authors.…”

Section: Discussionsupporting

confidence: 86%

“…Extensive fibrous connective tissue proliferation and dermal angiogenesis were also detected [4]. Multifocal degenerative changes in the articular surfaces (fibrosis, metaplasia of cartilage and bone), enlarged joints, thick friable Mans Vet Med J 21: 4 (2020) 132-141 tissue around the joint and severe articular erosions, a severe proliferation of fibrous connective tissue in /around articular surfaces, severe keratopathy with thick dull yellow exudate around the joints associated with mixed bacterial infection [5]. Also, measurement hematological parameters and CRP play a significant role in the diagnosis of this disease.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of turkey arthritis syndrome by traditional and advanced diagnostic techniques

Mowafy

Eldeen

2020

Mansoura Veterinary Medical Journal

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To detect possible causes of arthritis in turkey flocks with emphasis on molecular detection of bacterial pathogens and estimation of their pathology pattern. Design: Descriptive study Procedure: A total of 100 arthritic legs from 125 French turkey birds were collected from different farms in Sharkia Governorate. Specimens from joint capsule, tendons, and synovial fluid of leg joints were subjected to bacteriological and direct PCR examinations. Moreover, skin, cartilage of articular surface and epiphysis were undergone pathological examination. Blood samples were collected before scarification for both hematological and biochemical examinations. Results: Forty percent (40%) bacterial incidence rate including Staphylococcus spp., E. coli, Salmonella spp., Klebsiella spp., and Pseudomonas aeruginosa were recorded. Molecular detection of these pathogens revealed rapid and more accurate results of 46%. A high prevalence of multidrug resistance was detected, but all isolates were susceptible to amikacin and florfenicol. Genotyping of isolates revealed the presence of strong virulence markers. Postmortem examinations revealed joints swelling, hyperkeratosis, erosions,and/or ulcerations. Further investigations on positive infected samples revealed a significant decrease in RBCs, Hb, PCV %, lymphocytes, total protein, and albumin (P<0.05). However, there was a significant increase in total leukocytic count and heterophile, CRP, ALT, AST, uric acid, creatinine, and total globulin (P<0.05). Epidermal leukocytic cells infiltrations, tendonitis, synovium fibrosis, erosions, and/or ulcerations of articular cartilage were recorded. Conclusion: Turkey arthritis is a serious problem facing turkey flocks in Egypt. Multiplex real-time PCR assay offered an effective alternative to traditional typing methods for the identification of the etiological agents involved in the infectious arthritis in turkey.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

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Evaluation of turkey arthritis syndrome by traditional and advanced diagnostic techniques

Mowafy

Eldeen

2020

Mansoura Veterinary Medical Journal

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“…While OA is a prominent subject in mammalian clinical medicine and research, like osteogenesis itself, this condition has its counterpart in reptiles (Philbey, Lawrie, Alleson, & Taylor, 2006; Wolfe, Stringer, Krauss, & Trout, 2015) and birds (Degernes, Lynch, & Shivaprasad, 2011; Rothschild & Panza, 2007). Additionally, as demonstrated in the zebrafish model, the changes in morphology and gene expression in mammalian OA are present in fish at different developmental stages from larva to old age (Hayes et al, 2013; Mitchell et al, 2013).…”

Section: Evolution Of Oa Pathobiologymentioning

confidence: 99%

Osteoarthritis from evolutionary and mechanistic perspectives

Tangredi

Lawler

2019

The Anatomical Record

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Developmental osteogenesis and the pathologies associated with tissues that normally are mineralized are active areas of research. All of the basic cell types of skeletal tissue evolved in early aquatic vertebrates. Their characteristics, transcription factors, and signaling pathways have been conserved, even as they adapted to the challenge imposed by gravity in the transition to terrestrial existence. The response to excess mechanical stress (among other factors) can be expressed in the pathologic phenotype described as osteoarthritis (OA). OA is mediated by epigenetic modification of the same conserved developmental gene networks, rather than by gene mutations or new chemical signaling pathways. Thus, these responses have their evolutionary roots in morphogenesis. Epigenetic channeling and heterochrony, orchestrated primarily by micro-RNAs, maintain the sequence of these responses, while allowing variation in their timing that depends at least partly on the life history of the individual.

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“…Macroscopic lesions in brain tissues following the injection of partridges were mostly inapparent, but the histopathological examination of the brain tissue revealed congestion and thrombosis. Experimentally induced staphylococcosis as well as naturally occurring disease have been reported in chickens (Mutalib et al 1983a, McNamee et al 2000, Jiang et al 2015, turkeys (Linares et al 2001, Corrand et al 2012, pet birds (Briscoe et al 2008, Huynh et al 2014, Iverson et al 2015, birds of prey (Poorbaghi et al 2012, Bezjian 2014, waterfowl (Degernes et al 2011, Mondal et al 2014, and other avian species (Lemon et al 2012). The pathogenesis of systemic infection with Staphylococcus aureus in chukar partridge chicks is not clearly defined.…”

Section: Discussionmentioning

confidence: 99%