Degenerative and regenerative peripheral processes are associated with persistent painful chemotherapy-induced neuropathies in males and females
George T. Naratadam,
Jennifer Mecklenburg,
Sergey A. Shein
et al.
Abstract:This study aimed to investigate the time course of gene expression changes during the progression of persistent painful neuropathy caused by paclitaxel (PTX) in male and female mouse hind paws and dorsal root ganglia (DRG). Bulk RNA seq was used to investigate the gene expression changes in the paw and DRG collected at 1, 16, and 31 days post PTX. At these time points, differentially expressed DEGs were predominantly related to reduction or increase in epithelial, skin, bone, and muscle development and to angi… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.