Defying the odds: Determinants of the antimicrobial response of Salmonella Typhi and their interplay
Atish Roy Chowdhury,
Debapriya Mukherjee,
Ritika Chatterjee
et al.
Abstract:Salmonella Typhi, the invasive serovar of S. enterica subspecies enterica, causes typhoid fever in healthy human hosts. The emergence of antibiotic‐resistant strains has consistently challenged the successful treatment of typhoid fever with conventional antibiotics. Antimicrobial resistance (AMR) in Salmonella is acquired either by mutations in the genomic DNA or by acquiring extrachromosomal DNA via horizontal gene transfer. In addition, Salmonella can form a subpopulation of antibiotic persistent (AP) cells … Show more
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