Deformation Characteristics of a Bioabsorbable Intravascular Stent

Agrawal, C. Mauli; Clark, Haydn

doi:10.1097/00004424-199212000-00007

Cited by 33 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[7]. There are a number of biodegradable polymeric stents reported in the literature [8,9,10] with varying degrees of successes, but leaving several issues and/or limitations to be addressed. Most biodegradable polymeric stents are made with a zigzag structure, but there is no any optimal design method utilized.…”

Section: Introductionmentioning

confidence: 99%

“…This often causes weaker mechanical properties compared to native arterial vessels and result in early recoil post implantation [8]. In addition, the conventional methods of fabricating stents are typically to braid monofilaments of biodegradable polymer into a tubular structure [9,10], thus being time-consuming, expensive, and lacking precise control over the stent microstructure. Therefore, the conventional methods of fabricating stents result in poor repeatability and limit the design improvements that can be made.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments

Han

Kelly

et al. 2017

JFB

View full text Add to dashboard Cite

An aneurysm is a balloon-like bulge in the wall of blood vessels, occurring in major arteries of the heart and brain. Biodegradable polymeric stent-assisted coiling is expected to be the ideal treatment of wide-neck complex aneurysms. This paper presents the development of methods to fabricate and optimally design biodegradable polymeric stents for aneurysms treatment. Firstly, a dispensing-based rapid prototyping (DBRP) system was developed to fabricate coil and zigzag structures of biodegradable polymeric stents. Then, compression testing was carried out to characterize the radial deformation of the stents fabricated with the coil or zigzag structure. The results illustrated the stent with a zigzag structure has a stronger radial stiffness than the one with a coil structure. On this basis, the stent with a zigzag structure was chosen for the development of a finite element model for simulating the real compression tests. The result showed the finite element model of biodegradable polymeric stents is acceptable within a range of radial deformation around 20%. Furthermore, the optimization of the zigzag structure was performed with ANSYS DesignXplorer, and the results indicated that the total deformation could be decreased by 35.7% by optimizing the structure parameters, which would represent a significant advance of the radial stiffness of biodegradable polymeric stents.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments

Han

Kelly

et al. 2017

JFB

View full text Add to dashboard Cite

show abstract

“…Based on those properties, SMA stent can be designed to be applied in biomedical engineering fields. Many scholars studied applications of SMA stent in biomedical engineering [1][2][3][4]. Kaoriuri applied TiNi shape memory alloy foil in self-deployable origami stent grafts [1].…”

Section: Introductionmentioning

confidence: 99%

“…Kaoriuri applied TiNi shape memory alloy foil in self-deployable origami stent grafts [1]. Agrawal and Howard studied the deformation characteristics of a bioabsorbable intravascular stent [2]. Longas et al designed a New NiTi Stent and test its mechanical properties [3].…”

Section: Introductionmentioning

confidence: 99%

Nonlinear Dynamic Characteristics of SMA Intravascular Stent under Radial Stochastic Loads

Zhu

Zhang

Xu³

2014

Bio-Medical Materials and Engineering

View full text Add to dashboard Cite

Nonlinear dynamic characteristics of shape memory alloy (SMA) intravascular stent under radial stochastic loads were studied in this paper. Von de Pol item was improved to interpret the hysteretic phenomena of SMA, and the nonlinear dynamic model of SMA intravascular stent under radial stochastic loads was developed. The conditions of stochastic stability of the system were obtained in singular boundary theory. The steady-state probability density function of the dynamic response of the system was given, and the stochastic Hopf bifurcation characteristics of the system were analyzed. Theoretical analysis and numerical simulation show that the stability of the trivial solution varies with bifurcation parameters, and stochastic Hopf bifurcation appears in the process, which can cause stent fracture or loss. The results of this paper are helpful to application of SMA intravascular stent in biomedical engineering fields.

show abstract

“…Beyond that, no utility or advantage for permanent stents has been demonstrated. The advantages of a biodegradable stent include: (i) if a stent degrades and is absorbed by the body, it will not be an obstacle for future treatments and will not be a permanent potential nidus for infection; (ii) the gradual softening of the material would not only permit a smooth transfer of the load from the stent to the healing artery, but also would contravene the permanent imposition of extremely high stresses on the stented artery; and finally, (iii) a polymeric stent is a reservoir of appreciable size for the incorporation of drugs, and polymer 1 A note on terminology: Biodegradable polymers are polymers that are decomposed in the body, but whose degradation products remain in tissues. On the other hand, bioresorbable polymers can be defined as polymers that degrade after implantation into nontoxic products, which are then eliminated from the body or metabolized.…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Stents: Biomechanical Modeling Challenges and Opportunities

Moore

Soares

Rajagopal

2010

Cardiovasc Eng Tech

View full text Add to dashboard Cite

Biodegradable implants show great potential in many areas of medicine, and have already demonstrated success in simple applications such as sutures. For more complex devices, such as vascular stents, there are considerable challenges associated with the use of biodegradable materials. These materials typically are weaker than the metals currently used to construct stents, so it is difficult to ensure sufficient strength to prop open the artery and alleviate symptoms acutely. It is even more challenging to design a stent that provides structural support for a predictable, appropriate time to facilitate artery healing. These challenges are evident when one considers that there are no biodegradable stents on the US market despite more than 20 years of development efforts. This review summarizes previous efforts at implementing biodegradable stents, discusses the specific challenges involved, and presents a recently developed biodegradable material modeling framework that can benefit this exciting field.

show abstract

Deformation Characteristics of a Bioabsorbable Intravascular Stent

Cited by 33 publications

References 0 publications

Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments

Fabrication and Optimal Design of Biodegradable Polymeric Stents for Aneurysms Treatments

Nonlinear Dynamic Characteristics of SMA Intravascular Stent under Radial Stochastic Loads

Biodegradable Stents: Biomechanical Modeling Challenges and Opportunities

Contact Info

Product

Resources

About