Deflected Capillary Force Lithography

Cai, Yuzhe; Zhao, Zhi; Chen, Jixin; Yang, Tinglu; Cremer, Paul S.

doi:10.1021/nn2045278

Cited by 24 publications

(29 citation statements)

References 43 publications

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“…33 The mechanism for the formation of asymmetric rings is caused by the deflection of cylindrical pillars protruding from the PDMS mould. A typical deflected CFL is carried out by placing a PDMS wedge with an angle, ω, on the PDMS mould.…”

Section: Deflected Cflmentioning

confidence: 99%

Capillary force lithography: the versatility of this facile approach in developing nanoscale applications

Zou

Zdyrko

et al. 2015

Nanoscale

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Since its inception as a simple, low cost alternative to more complicated lithographic techniques such as electron-beam and dip-pen lithography, capillary force lithography (CFL) has developed into a versatile tool to form sub-100 nm patterns. Utilizing the concept of a polymer melt, structures and devices generated by the technique have been used in applications varying from surfaces regulating cell growth to gas sensing. In this review, we discuss various CFL methodologies which have evolved, their application in both biological and non-biological research, and finally a brief outlook in areas of research where CFL is destined to make an enormous impact in the near future.

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Section: Deflected Cflmentioning

confidence: 99%

Capillary force lithography: the versatility of this facile approach in developing nanoscale applications

Zou

Zdyrko

et al. 2015

Nanoscale

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“…When the capillary tubes are wet with some liquid, the wetting will results in the capillary rise of the liquid because of the the free energy lower by the wetting [18][19][20]. This phenomenon has been used as a method called micromolding in capillaries [21][22][23][24][25]. Using the capillary molding process with the curing, the molds of the different sizes, the desired surface structures are created by the heating or UV radiation [26,27].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Hydrophobic Micro-lens Arrays by Capillary Force Lithography

Xu¹,

Xu²,

Wang³

et al. 2017

dteees

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Abstract. This paper presents a method based on the capillary force lithography technology to fabricate the micro-lens arrays. The micro-lens arrays characterized with hydrophobic were obtained by combining this capillary force lithography and photolithography. In the method, the PDMS is used as an elastomeric mold that has a planar surface with the negative concave micro-lens structures by casting PDMS against a complementary relief structure prepared by photolithography. The imaging and the hydrophobic performances of the micro-lens array are achieved during the experiments, and the maximum contact angle reaches 124° approximately. This technology is suitable for applications required a self-cleaning surface such as image sensors and detectors operating under the natural conditions.

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“…9–10 Another similar technique is capillary force lithography that combines imprint lithography with microcontact printing, or other methods of soft lithography. 11–13 In contrast, EEL involves micro and nanostructure generation by solvent evaporation and allows integration of multiple materials onto the surface. These subcellular lipid multilayer structures have applications in biosensing 1, 14 and high throughput screening.…”

Section: Introductionmentioning

confidence: 99%

Evaporative edge lithography of a liposomal drug microarray for cell migration assays

et al. 2015

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Lipid multilayer microarrays are a promising approach to miniaturize laboratory procedures by taking advantage of the microscopic compartmentalization capabilities of lipids. Here, we demonstrate a new method to pattern lipid multilayers on surfaces based on solvent evaporation along the edge where a stencil contacts a surface called evaporative edge lithography (EEL). As an example of an application of this process, we use EEL to make microarrays suitable for a cell-based migration assay. Currently existing cell migration assays require a separate compartment for each drug which is dissolved at a single concentration in solution. An advantage of the lipid multilayer microarray assay is that multiple compounds can be tested on the same surface. We demonstrate this by testing the effect of two different lipophilic drugs, Taxol and Brefeldin A, on collective cell migration into an unpopulated area. This particular assay should be scalable to test of 2000 different lipophilic compounds or dosages on a standard microtiter plate area, or if adapted for individual cell migration, it would allow for high-throughput screening of more than 50,000 compounds per plate.

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Deflected Capillary Force Lithography

Cited by 24 publications

References 43 publications

Capillary force lithography: the versatility of this facile approach in developing nanoscale applications

Capillary force lithography: the versatility of this facile approach in developing nanoscale applications

Fabrication of Hydrophobic Micro-lens Arrays by Capillary Force Lithography

Evaporative edge lithography of a liposomal drug microarray for cell migration assays

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