Definitions of Urinary Tract Infection Used in Interventional Studies Involving Neurourological Patients—A Systematic Review

Sartori, Andrea; Padilla‐Fernández, Bárbara; Hoen, Lisette A. ’t; Blok, Bertil; Castro-Díaz, David Manuel; Popolo, Giulio Del; Musco, Stefania; Hamid, Rizwan; Ecclestone, Hazel; Groen, Jan; Karsenty, G.; Phé, Véronique; Kessler, Thomas M.; Pannek, Jürgen

doi:10.1016/j.euf.2021.07.012

Cited by 13 publications

(8 citation statements)

References 62 publications

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“…On the other hand, CAUTI was asymptomatic in critically ill patient that reported by Weiss, et al (2019) (35) Concerning blood chemistry. (36) In -Assessment of problems facing critical care nurse regarding hygienic and catheter care and their effect on nurses' performance and satisfaction.…”

Section: Methods Of Data Analysismentioning

confidence: 99%

“…Its results revealed that total of 2022 patients were hospitalized in ICUs and acquired length of hospital stay more than 15 days. (5) Catheter-associated urinary tract infection is defined as a urinary tract infection that occurs among patients with an indwelling urinary catheter, where was in place for >2 days, at least one of the following signs or symptoms: fever (>38.0°C, suprapubic tenderness ,costovertebral angle pain or tenderness ,urinary urgency ,urinary frequency ,dysuria , Patient has a urine culture with no more than two species of organisms identified, at least one of which is a bacterium of ≥105 CFU/ml (6) Several strategies have been used by healthcare specialists to deal with and prevent the risk of CA-UTIs among critically ill patients. These methods include hand hygiene practices, methods of handling indwelling catheter, urine collecting system.appropriately, securing catheter properly, maintaining unobstructed urine flow and closed sterile drainage system, However, the application of antiseptic chlorhexidine gluconate 2% bathing for the critically ill patients is the most proper method for controlling the source of CAUTIs infection.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of Protocol of Hygienic Care by Chlorhexidine Gluconate on the Occurrence of Catheter Associated Urinary Tract Infection among Critical Ill Patients

Hak

Sahban

din

et al. 2022

Tanta Scientific Nursing Journal

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Catheter-associated urinary tract infections (CAUTIs) is the most common type of hospital acquired infection in Intensive Care Units. It is associated with significant morbidity, length of hospital stay and cost of hospitalization. Preventing CAUTI is essential and critical care nnurses are the key to accomplishing this goal. Aim: -evaluate the efficacy of protocol of hygienic care by chlorhexidine gluconate on the occurrence of a catheter associated urinary tract infection among critically ill patients. Desgin and setting: -A quasi-experimental study was conducted at the Neurological Intensive Care Unit of both Tanta University Hospital and Neuro-psychiatry center at Tanta Main University Hospital. A convenience sampling of 60 adult patients with indwelling urinary catheters were selected and divided into two equal groups 30 patients in each group. Group 1:-(Control group), they received routine nursing care by hospital nursing staff. Group 2:-(Study group), they received application of protocol of hygienic care by cholorohexidine gluconate 2%. Three tools were used for data collection .Tool (I) Assessment tool which included Patient's socio-demographic characteristics. Tool (II)): Catheter Associated Urinary Tract Infection Assessment Profile (CAP):-. Tool (III)): Infection Assessment Sheet: -. Results: -The main results revealed that the incidence rate of CAUTI among control group subjects was 93.33% while among study group subjects was 40.00%.Conclusions and recommendations: -Application of protocol of daily Hygienic Care by Chlorhexidine Gluconate has a significance effectiveness on reducing CAUTI among critically ill patients .It was recommended that all critically -ill patients with indwelling urinary catheter in ICU should receive daily Hygienic Care by Chlorhexidine Gluconate as routine of care.

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Section: Methods Of Data Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Efficacy of Protocol of Hygienic Care by Chlorhexidine Gluconate on the Occurrence of Catheter Associated Urinary Tract Infection among Critical Ill Patients

Hak

Sahban

din

et al. 2022

Tanta Scientific Nursing Journal

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“…The hospital laboratory follows the UK Standards for Microbiological Investigation for examination of urine, reporting a urine culture as positive when caused by a single organism that is present in a concentration of ≥ 10 5 CFU/ml. 13 Urine culture results were available for those urine tests sent by the hospital and by the majority of local general practices who are geographically near the hospital and as such utilise the hospital laboratory. Most patients referred to our hospital live within the catchment area for the hospital laboratory.…”

Section: Methodsmentioning

confidence: 99%

Urinary tract infections in the intradetrusor onabotulinumtoxinA population

White,

Brewin,

Nitkunan

2023

UIJ

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The aim of our study was to determine the incidence of Urinary Tract Infections (UTI) following intradetrusor onabotulinumtoxinA injections within our trust. This was a retrospective study of all patients who underwent intradetrusor onabotulinumtoxinA injections at our trust from August 2005 to 2015. Information was taken from our botulinum database, clinic letters and microbiology results. The primary outcome criterion was a positive urine culture together with symptoms suggestive of infection within 6 months post-procedure. A total of 290 intradetrusor onabotulinumtoxinA procedures were performed on 86 patients. The rate of UTI within 6 months following a procedure was 33%. There was a high resistance rate to our standard antibiotic prophylaxis, which was changed together with the addition of pre-procedure urine cultures and an on the day urine dipstick test. A re-audit was performed between January and June 2016 of 41 procedures and showed a reduction in UTI incidence to 20%. The rate of UTI post procedure within our trust was 33%. Following the implementation of multiple management protocol changes, a re-audit showed a reduction of UTI incidence to 20%.

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“…Patients may be biologically heterogeneous in terms of symptoms, or by having different etiologies leading to similar phenotypes that are then diagnosed as belonging to the same disease, but clinical heterogeneity is also an important factor, as non-standardized clinical input and outcome measures create technical variation that obscures disease progression of treatment response, making tracking of these processes difficult. For instance, with respect to urinary tract infections (UTI), there has been a lack of standardization in the definition of UTIs in neuro-urological patients [ 46 ]. This lack of standardization is also found in other patient cohorts [ 47 , 48 ].…”

Section: Applications Of Biobanking In Neuro-urologymentioning

confidence: 99%

Neuro-Urology and Biobanking: An Integrated Approach for Advancing Research and Improving Patient Care

Botter,

Kessler

2023

IJMS

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Understanding the molecular mechanisms underlying neuro-urological disorders is crucial for the development of targeted therapeutic interventions. Through the establishment of comprehensive biobanks, researchers can collect and store various biological specimens, including urine, blood, tissue, and DNA samples, to study these mechanisms. In the context of neuro-urology, biobanking facilitates the identification of genetic variations, epigenetic modifications, and gene expression patterns associated with neurogenic lower urinary tract dysfunction. These conditions often present as symptoms of neurological diseases such as Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, spinal cord injury, and many others. Biobanking of tissue specimens from such patients is essential to understand why these diseases cause the respective symptoms and what can be done to alleviate them. The utilization of high-throughput technologies, such as next-generation sequencing and gene expression profiling, enables researchers to explore the molecular landscape of these conditions in an unprecedented manner. The development of specific and reliable biomarkers resulting from these efforts may help in early detection, accurate diagnosis, and effective monitoring of neuro-urological conditions, leading to improved patient care and management. Furthermore, these biomarkers could potentially facilitate the monitoring of novel therapies currently under investigation in neuro-urological clinical trials. This comprehensive review explores the synergistic integration of neuro-urology and biobanking, with particular emphasis on the translation of biobanking approaches in molecular research in neuro-urology. We discuss the advantages of biobanking in neuro-urological studies, the types of specimens collected and their applications in translational research. Furthermore, we highlight the importance of standardization and quality assurance when collecting samples and discuss challenges that may compromise sample quality and impose limitations on their subsequent utilization. Finally, we give recommendations for sampling in multicenter studies, examine sustainability issues associated with biobanking, and provide future directions for this dynamic field.

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Definitions of Urinary Tract Infection Used in Interventional Studies Involving Neurourological Patients—A Systematic Review

Cited by 13 publications

References 62 publications

Efficacy of Protocol of Hygienic Care by Chlorhexidine Gluconate on the Occurrence of Catheter Associated Urinary Tract Infection among Critical Ill Patients

Efficacy of Protocol of Hygienic Care by Chlorhexidine Gluconate on the Occurrence of Catheter Associated Urinary Tract Infection among Critical Ill Patients

Urinary tract infections in the intradetrusor onabotulinumtoxinA population

Neuro-Urology and Biobanking: An Integrated Approach for Advancing Research and Improving Patient Care

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