Definition of Intertwin Birth Weight Discordance

Breathnach, Fionnuala; McAuliffe, Fionnuala M.; Geary, Michael; Daly, Seán; Higgins, John R.; Dornan, James; Morrison, John J.; Burke, Gerald; Higgins, Shane; Dicker, Patrick; Manning, Fiona; Mahony, Rhona; Malone, Fergal D.

doi:10.1097/aog.0b013e31821fd208

Cited by 128 publications

(145 citation statements)

References 19 publications

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“…In addition because dizygotic twins are genetically distinct individuals, it is not surprising that they might be programmed to have very different weights at birth. In this regard discordance up to 10 percent can be considered normal [2]. With increasing discordance (>18%) the risk of adverse perinatal outcome remains increased within a growth-discordant pair even where both twins were appropriate for gestational age [2].…”

Section: Discussionmentioning

confidence: 99%

“…In this regard discordance up to 10 percent can be considered normal [2]. With increasing discordance (>18%) the risk of adverse perinatal outcome remains increased within a growth-discordant pair even where both twins were appropriate for gestational age [2]. Weather discordant pairs where one or both of the foetuses were large for gestational ages are at risk of adverse effect is not known, as this is rare occurrence in twins.…”

Section: Discussionmentioning

confidence: 99%

“…One of these complications, growth abnormality, is common and manifest as: either one or both twins being small for gestational age or one twin can be significantly smaller than the other twin (i.e., growth discordance) [1,2]. Discordance in birth weight of >20 percent is the most commonly used threshold considered to be predictive of adverse outcome and present in 15 percent of twins [1].…”

Section: Introductionmentioning

confidence: 99%

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Macrosomia in Discordant Twin: An Out of the Box Presentation of Abnormal Growth in Dizygotic Twin

Assefa¹,

Woldeyes²

2015

Gynecol Obstet (Sunnyvale)

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Background: Weight discordance of ≥ 20 percent is present in 15 percent of twin pairs and mostly the smaller twin's birth weight <10 th percentile and the larger twin is nearer appropriate size for gestational age. We report twin pairs where the larger twin is macrosomic with smaller twin having normal birth weight. We could not find a similar report in the literature.Case presentation: The twins were born to 29 years old gravida 3 para 2 lady at 38 weeks and 3 days of gestation. The first of twins was male and macrosomic (4500 gm) and his twin sister was of normal birth weight (3500 gm), with 22 percent birth weight discordance. Conclusion:We report this case as there is no similar report in the literature on abnormal growth of twins with macrosomia and discordance: an out of the box presentation. Both of our cases are large for gestational age an adjustable fetal weight standard for twins.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Macrosomia in Discordant Twin: An Out of the Box Presentation of Abnormal Growth in Dizygotic Twin

Assefa¹,

Woldeyes²

2015

Gynecol Obstet (Sunnyvale)

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“…In a large, multicenter, prospective study (ESPRiT) [3] the cut-off value of the EFW discordance above which, the risk for poor perinatal outcomes becomes 2-fold more than the risk in singleton pregnancies, stands at 18% for both dichorionic twins and monochorionic twins without cases of twin-to-twin transfusion syndrome. However, the same study reaches the conclusion that discordant monochorionic twins face higher absolute morbidity risks in comparison with discordant dichorionic twins at all stages of birth weight discordance [3].…”

Section: Estimated Fetal Weight Discordance and Perinatal Outcomementioning

confidence: 99%

“…However, monochorionic twin pregnancies are complicated by such discordances twice as often as dichorionic ones. Higher degrees of growth discordance are accompanied by higher rates of perinatal mortality and morbidity both in the smaller and in the larger twin [3][4][5]. The current review serves to explore the importance of inter-twin estimated fetal weight (EFW) and crown rump length (CRL) discordance for the prediction of adverse perinatal outcome.…”

Section: Introductionmentioning

confidence: 99%

Intertwin estimated fetal weight or crown rump length discordance and adverse perinatal outcome

Kaponis

Thanatsis

Papadopoulos

et al. 2015

Journal of Perinatal Medicine

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Aim: In the current review study, we present recent data regarding the importance of intertwin estimated fetal weight (EFW) and crown rump length (CRL) discordance for the prediction of adverse perinatal outcome both in monochorionic and in dichorionic diamniotic gestations. Results: Twins with significant weight disparity are associated with higher rates of perinatal morbidity and mortality, regardless of gestational age at delivery. However, there is no agreement regarding as to the cut off value above which the perinatal outcome is unfavorably affected and the threshold range from 10 to 30%. On the other hand, CRL discrepancy has proved to be a weak predictor of adverse outcomes, such as fetal or neonatal death in fetuses without chromosomal and structural abnormalities. In clinical practice, decisions about obstetric surveillance of discordant twin gestations, frequency of fetal sonographic monitoring and time of delivery are usually based on amniotic fluid volume and Doppler assessments on a weekly basis. Conclusion: Significant EFW discordance leads to adverse perinatal outcome, although the cut-off value has not yet been estimated. CRL discrepancy is not correlated well with adverse perinatal outcome. However, increased monitoring of women with EFW and CRL discrepancy is suggested.

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Definition of Intertwin Birth Weight Discordance

Cited by 128 publications

References 19 publications

Macrosomia in Discordant Twin: An Out of the Box Presentation of Abnormal Growth in Dizygotic Twin

Macrosomia in Discordant Twin: An Out of the Box Presentation of Abnormal Growth in Dizygotic Twin

Intertwin estimated fetal weight or crown rump length discordance and adverse perinatal outcome

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