Abstract:Neutrophils are typically considered short-lived and terminally differentiated. However, recent studies have identified a poorly understood neutrophil subset that can differentiate into dendritic cells and become long-lasting “hybrids” of neutrophils and dendritic cells. These neutrophil-dendritic cells (PMN-DCs) maintain the functions of canonical neutrophils while gaining antigen-presenting properties of dendritic cells, enabling them to contribute to both innate and adaptive immunity. Although PMN-DCs have … Show more
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