Deficits in Movement Planning and Intrinsic Coordinate Control in Ideomotor Apraxia

Jax, Steven A.; Buxbaum, Laurel J.; Moll, Adrienne D.

doi:10.1162/jocn.2006.18.12.2063

Cited by 50 publications

(52 citation statements)

References 53 publications

(70 reference statements)

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“…Like the majority of motor control studies in people post stroke, we excluded people who had significant aphasia, hemi-neglect, and/or cognitive dysfunction. Thus our results may be biased away from those individuals with the most obvious motor planning deficits such as apraxia (Jax et al 2006). Our subjects were recruited based on the clinical presence of hemiparesis and not based on specific lesion locations.…”

Section: Contributions Of Digit Extension Ability To Graspingmentioning

confidence: 99%

Recovery of Thumb and Finger Extension and Its Relation to Grasp Performance After Stroke

Lang¹,

DeJong²,

Beebe³

2009

Journal of Neurophysiology

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Lang CE, DeJong SL, Beebe JA. Recovery of thumb and finger extension and its relation to grasp performance after stroke. J Neurophysiol 102: 451-459, 2009. First published May 20, 2009 doi:10.1152/jn.91310.2008. This study investigated how the ability to extend the fingers and thumb recovers early after stroke and how the ability to extend all of the digits affects grasping performance. We studied 24 hemiparetic patients at 3 and 13 wk post stroke. At each visit, we tested the subjects' ability to actively extend all five digits of their contralesional, affected hand against gravity and to perform a grasp movement with the same hand. Three-dimensional motion analysis captured: 1) maximal voluntary extension excursion of each digit and 2) grasp performance variables of movement time, peak aperture, peak aperture rate, and aperture path ratio. We found that finger and thumb extension improved from 3 to 13 wk, with average improvements ranging from 12 to 19°across the five digits. Grasp performance improved on two of the four variables measured. Peak apertures and peak aperture rates improved from 3 to 13 wk, but self-selected movement time and aperture path ratio did not. Stepwise multiple regression models showed that the majority of variance in grasp performance at 13 wk could be predicted by the ability to extend the index or middle finger at 3 wk, plus the change in the ability to extend the index finger from 3 to 13 wk. R 2 values ranged from 0.55 to 0.89. Our data indicate that the amount of recovery in finger and thumb extension and grasping is small from 3 to 13 wk post stroke. In people with relatively pure motor hemiparesis, one important factor underlying deficits in hand shaping during grasping is the inability to extend the fingers and thumb. Without sufficient volitional control of finger and thumb extension, successful grasping of objects will not occur.

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Section: Contributions Of Digit Extension Ability To Graspingmentioning

confidence: 99%

Recovery of Thumb and Finger Extension and Its Relation to Grasp Performance After Stroke

Lang¹,

DeJong²,

Beebe³

2009

Journal of Neurophysiology

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“…The intrinsic/extrinsic (IE) task was an abbreviated version of the meaningless imitation task used by Jax et al (2006), and was used to test predictions about both deficits in intrinsic coordinate control and abnormal reliance on visual feedback. In the task, videos of an actor making a movement to a static end position were presented on a computer screen approximately 150 cm in front of the seated participant.…”

Section: Methodsmentioning

confidence: 99%

“…placing a vertically oriented hand to the side of the head; De Renzi, 1985; Goldenberg & Hagmann, 1997). We have previously linked such deficits to a disruption of the motor system’s control of movement in an intrinsic coordinate frame (Buxbaum, Giovannetti, & Libon, 2000; Buxbaum, 2001; Jax, Buxbaum, & Moll, 2006). Intrinsic coordinate control specifies movement plans in terms of body position (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Evidence from a range of tasks indicates that the nervous system may use both forms of control in a flexible task-dependent manner (Brayanov, Press, & Smith, 2012; Meghani, Burgess, & Patton, 2009; Parmar, Huang, & Patton, 2011). On our previous account (Jax et al, 2006), apraxics may be impaired at imitating meaningless body postures because such postures are defined by body positions and would logically be performed most efficiently using body-based intrinsic coordinate control. In contrast, tasks that are less impaired in patients with apraxia, such as reaching and grasping for an object in the workspace (Buxbaum, Johnson-Frey, & Bartlett-Williams, 2005), would logically be more efficiently controlled using extrinsic coordinates (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Apraxics have been reported to exhibit deficits in multiple forms of movement planning, including end posture selection (Buxbaum, Johnson-Frey, et al, 2005), the time required to complete movements (Sirigu et al, 1996), and accounting for intersegmental dynamics (Mutha, Sainburg, & Haaland, 2010). These planning deficits may be partially compensated by an over-reliance on visual feedback (Buxbaum, Johnson-Frey, et al, 2005; Haaland, Harrington, & Knight, 1999; Jax et al, 2006). Because visual feedback of a tool’s motion is absent, PTU may rely relatively strongly on feedforward movement planning, rendering it particularly challenging for apraxics.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Conceptual- and production-related predictors of pantomimed tool use deficits in apraxia

2014

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Apraxia following left hemisphere stroke disrupts pantomimed tool use (PTU), a task that requires the integrity of a number of cognitive and motor processes. Although previous studies have identified that apraxics have deficits in (1) the integrity of/access to stored tool-use gesture representations, (2) deficits in intrinsic (body-based) coordinate control, and (3) abnormal reliance on visual feedback, no study to date has simultaneously tested the relative contribution of these three deficits to poor PTU performance. In this study we assessed 38 chronic left hemisphere stroke survivors on tests of PTU and the 3 component processes. We then attempted to predict PTU with the component scores using hierarchical regression to control for overall stroke severity and the possibility of correlated component scores. Results showed that over half of the variability in PTU was predictable, with the strongest independent predictor being a test of intrinsic coordinate control without visual feedback. A test of the integrity of/access to stored representations also predicted PTU. These results confirm and extend previous claims that conceptual- and production-related factors affect PTU, even after considering that deficits in both factors are commonly observed to varying degrees in apraxic patients.

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Disorders of the Perceptual-Motor System

Jax

Coslett²

2009

Advances in Experimental Medicine and Biology

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The study of patients with movement disorders provides insight into both the functional organization and the neural substrates of the perceptual-motor system. By and large, we feel this source of information has been underutilized within the basic science of motor control. To begin to address this shortcoming, this chapter reviews three disorders of the perceptual-motor system (disorders of the body schema, optic ataxia, and ideomotor apraxia) and illustrates how the study of these disorders can inform central issues within the field of motor control. These issues include (1) the need for the perceptual-motor system to maintain a representation of the body's current configuration in order to produce movements, (2) the use of visual information in movement production, (3) the coordinate frame in which movements are controlled, (4) the distinction between movement planning and online correction, and (5) the role of the parietal cortex in action. In the conclusion, we discuss several limitations of studying patients with movement disorders as well as suggest that greater communication is needed between researchers in the basic science of motor control and clinicians developing treatments for movement disorders.

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Deficits in Movement Planning and Intrinsic Coordinate Control in Ideomotor Apraxia

Cited by 50 publications

References 53 publications

Recovery of Thumb and Finger Extension and Its Relation to Grasp Performance After Stroke

Recovery of Thumb and Finger Extension and Its Relation to Grasp Performance After Stroke

Conceptual- and production-related predictors of pantomimed tool use deficits in apraxia

Disorders of the Perceptual-Motor System

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