Deficiency of SR‐B1 reduced the tumor load of colitis‐induced or APCmin/+‐induced colorectal cancer
Qijun Chen,
Lixue Wang,
Hui Song
et al.
Abstract:BackgroundColorectal cancer (CRC) is one of the most common tumors in the world. Cholesterol plays an important role in the pathogenesis of tumors. One of the cholesterol transporters, scavenger receptor class B type 1 (SR‐B1), a multi‐ligand membrane receptor protein, is expressed in the intestines which also highly expressed in various tumors. But the potential mechanism of SR‐B1 in CRC development has not been reported.AimsThis study aimed to clarify the importance of SR‐B1 in the development and prognosis … Show more
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