Deficiência de ferro: ainda a principal etiologia entre crianças encaminhadas por motivo de anemia para serviço especializado de hematologia

Santana, Marcio Antônio Portugal; Norton, Rocksane de Carvalho; Fernandes, Rachel Aparecida Ferreira

doi:10.1590/s1519-38292009000300010

Cited by 1 publication

(1 citation statement)

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“…Even if sickle cell anemia and thalassemias are not responsible for the difference found in hemoglobin levels between whites and blacks, hemoglobinopathies should be investigated, especially in cases where there is no positive response to treatment with ferrous sulphate. According to Santana et al 20 , 16% of children referred to the Pediatric Hematology Service of the General Hospital of the Federal University of Minas Gerais (UFMG), due to poor response to treatment with oral iron, are diagnosed with β-thalassemia.…”

Section: Introductionmentioning

confidence: 99%

Differences in the hemoglobin cut-off point for the diagnosis of anemia as a function of race/color

Sperandio¹,

Sant’Ana²,

Franceschini³

et al. 2015

Revista Médica De Minas Gerais

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Hemoglobin levels vary according to age, gender, different phases of pregnancy, smoking habit, and altitude. In the early 90s, researchers began to notice unexplained differences in hemoglobin levels between whites and blacks in various age groups. Since then, studies began to be published to identify which factors would be responsible for such differences. From a review of the literature, we aimed at exposing relevant aspects that may assist in the understanding of why blacks have lower levels of hemoglobin in relation to whites. The Medline, Lilacs, and Pubmed databases were used for this review. Studies have shown that the levels of hemoglobin in blacks are lower, ranging between 0.5 and 1 g/dL in relation to whites. This difference remains, even controlling for possible confounding factors such as intake and iron nutritional status, socioeconomic status, age, and comorbidities among others. The studies, however, do not come to a conclusion about what raises this difference between races. Therefore, proposing specific cutoff points as a function of race, as some authors suggest, may be precipitated and result in not identifying people with anemia, which is considered a serious public health problem in Brazil.

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Section: Introductionmentioning

confidence: 99%