Defibrillation threshold (DFT) estimation with fewer VF inductions during ICD testing: Application of Upper Limit of Vulnerability (ULV) guided shock on T induction protocol in pediatrics

Efficacy of Tuned Waveforms Based on Different Membrane Time Constants on Defibrillation Thresholds: Primary Results from the POWER Trial

“…Sedation for DFT testing was left to the physician's choice because the endpoint was a pairwise comparison in the same patient during a single implant procedure. To reduce the number of ventricular fibrillation (VF) inductions for comparison of various tuned waveforms, the upper limit of vulnerability (ULV)‐guided DFT testing methodology was utilized in the study 16,17 . Two sets of DFT testing were performed at implant or within 30 days postimplant.…”

“…We used a hybrid ULV/induction method to derive the DFT estimate to obtain fairly precise estimates while minimizing the number of VF inductions 16,17 . Our approach was similar to that of the TULIP trial 19 …”