Defensive Secretions of Millipeds

Eisner, Thomas; Alsop, D. W.; Hicks, Karen; Meinwald, Jerrold

doi:10.1007/978-3-642-45501-8_3

Cited by 98 publications

(125 citation statements)

References 66 publications

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“…The secretions include different quinones, phenolic compounds, organic acid, quinazolines, monoterpens, or cyanogenic compounds (Eisner et al, 1978). Chemical studies indicate that the quantitative and qualitative differences in millipede allomones show some phylogenetic patterns.…”

Section: Resultsmentioning

confidence: 99%

Chemical defense in the cave-dwelling millipede Brachydesmus troglobius Daday, 1889 (Diplopoda, Polydesmidae)

Makarov¹,

Vujisić²,

Ćurčić³

et al. 2012

IJS

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Section: Resultsmentioning

confidence: 99%

Chemical defense in the cave-dwelling millipede Brachydesmus troglobius Daday, 1889 (Diplopoda, Polydesmidae)

Makarov¹,

Vujisić²,

Ćurčić³

et al. 2012

IJS

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“…Many juliform millipedes (superorder Juliformia) passively ooze chemicals from their repugnatorial glands on intruders, but some larger species in the orders Spirobolida and Spirostreptida can also eject their secretions on assailants from distances as far as fifty centimeters away [49].…”

Section: Bioactive Compounds From Araneaementioning

confidence: 99%

“…However, extinct millipedes from the genus Arthropleura Meyer, 1854 (in the extinct class Arthropleuridea) from the late Carboniferous (315 to 299 million years ago) was giant in size, having reached up to three meters in length and forty-six centimeters in width [188]. Most myriapods are generally not considered dangerous to humans, but many produce noxious secretions which can cause temporary blistering and discoloration of the skin [49][50][51].…”

Section: Myriapodamentioning

confidence: 99%

Exploring the global animal biodiversity in the search for new drugs – Spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes

Mans¹

2017

J Transl Sci

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Drug discovery and development programs have historically mainly focused on plants with medicinal properties and the extensive knowledge of traditional healers about these plants. More recently, the vast array of marine invertebrates and insects throughout the world have been recognized as additional sources for identifying unusual lead compounds to obtain structurally novel and mechanistically unique therapeutics. The results from these efforts are encouraging and have yielded a number of clinically useful drugs. However, many arthropods other than insects -such as spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes -also produce hundreds of bioactive substances in their venom that may become useful in the clinic. Many of these chemicals are defensive and predatory weapons of these creatures and have been refined during millions of years of evolution to rapidly and with high specificity and high affinity shut down critical molecular targets in prey and predators. Exploration of these compounds may lead to the development of, among others, novel drugs for treating diseases caused by abnormalities in humans in the same (evolutionary conserved) molecular targets such as erectyle dysfunction, botulism, and autoimmune disorders, as well as the identification of novel antineoplastic, antimicrobial, and antiparasitic compounds. This paper addresses the importance of bioactive compounds from spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes to these advances.

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“…They are present in defensive secretions of Diplopoda (EISNER et al 1978), Isoptera (see later), Orthoptera, Dermaptera, Dictyoptera, Thysanoptera, Coleoptera, and Opiliones (WHITMAN et al 1990) as well as in termite resistant timbers (FLOYD et al 1976, LEISTNER 1985. It seems strange that such effective repellents act as attractants for some insects.…”

Section: Quinones and The Feeding Ecology Of Oryctinimentioning

confidence: 99%

The rhinoceros beetleCyphonistes tuberculifronsQuedenfeldt 1884 attracted by quinones (Coleoptera Scarabaeidae Dynastinae): primary olfactory attraction of a saprophagous beetle by its source of food?

1999

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Defensive Secretions of Millipeds

Cited by 98 publications

References 66 publications

Chemical defense in the cave-dwelling millipede Brachydesmus troglobius Daday, 1889 (Diplopoda, Polydesmidae)

Chemical defense in the cave-dwelling millipede Brachydesmus troglobius Daday, 1889 (Diplopoda, Polydesmidae)

Exploring the global animal biodiversity in the search for new drugs – Spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes

The rhinoceros beetleCyphonistes tuberculifronsQuedenfeldt 1884 attracted by quinones (Coleoptera Scarabaeidae Dynastinae): primary olfactory attraction of a saprophagous beetle by its source of food?

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