Defect-engineered transition metal hydroxide nanosheets realizing tumor-microenvironment-responsive multimodal-imaging-guided NIR-II photothermal therapy

Abstract

Exploiting two-dimensional nanomaterials as photo-based theranostic agent has witnessed great promise in highly effective ablation of deep-tissue buried tumors. However, it’s still limited by their poor absorption in the second...

NIR-II Functional Materials for Photoacoustic Theranostics

“…In addition, it could also be used for MRI contrast agents because of the inherent paramagnetism. 64 A family of thiadiazolinoline-based (TQ) semiconductor polymers (SPs) had wide absorbance from NIR-I to NIR-II. Among them, s-BDT-TQE, as the SPs repeating unit, exhibited a larger dihedral angle, a narrower adiabatic energy, and a lower radiation attenuation because of the strong electrondeficient ester replacing TQ segment (Figure 7d).…”

Smart intercalation and coordination strategy to construct stable ratiometric fluorescence nanoprobes for the detection of anthrax biomarker

“…39,40 Therefore, such unique structures with an atomic level distribution of metal cations and excellent anion exchange intercalation properties allow the LDHs to have versatile applications, as catalysts, 41,42 adsorbents, 43,44 biology 39,45,46 and nanoreactors. [47][48][49] Remarkably, lanthanide-functionalized LDHs with a homogeneous distribution of lanthanide ions and synergistic effects tend to provide excellent optical materials. [50][51][52] In particular, ratiometric fluorescent DPA nanosensors were successfully constructed by intercalating organic chromophores with anionic groups into the lanthanide-based LDH interlayer.…”

Simultaneous one-step regulation of planarization and donor rotation to enhance multi-modal imaging guided therapy

“…[21][22][23] Besides, PAI and PTI can also obtain images with high resolution and contrast, originating from the thermal and acoustic wave signals during vibration relaxation. 24,25 Therefore, optimizing the structure of PSs was studied to balance radiation and non-radiation transitions for improving the performance on imaging and therapy. Recently, Tang et al proposed a strategy for improving Type I ROS and photothermal conversion efficiency by increasing the acceptor planarization and donor rotation, which has guiding significance to develop high-efficacy Type I theranostic agents.…”