Defatted flaxseed flour improves weight loss and lipid profile in overweight and obese adults: a randomized controlled trial

Kuang, Xiaotong; Kong, Yan; Hu, Xiaojie; Li, Duo; Guo, Xiaofei; Liu, Chunxiao; Han, Lei; Li, Duo

doi:10.1039/d0fo00838a

Cited by 14 publications

(20 citation statements)

References 36 publications

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“…Other authors reported that whole flaxseed or products with flaxseed or flaxseed oil could improve TG concentration [ 46 , 64 , 65 , 66 ]. In 2020, a double-blind randomized trial in 53 overweight and obese patients found an improvement in TG after 60 days of intervention with 100 g/day of biscuits with flaxseed meal (105 ± 51.63 mg/dL (20 ± 0.59 mmol/L) vs. 101.5 ± 55.13 mg/dL (1.16 ± 0.63 mmol/L); p < 0.005).…”

Section: Foodsmentioning

confidence: 99%

The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence

et al. 2022

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Approximately 25–50% of the population worldwide exhibits serum triglycerides (TG) (≥150 mg/dL) which are associated with an increased level of highly atherogenic remnant-like particles, non-alcoholic fatty liver disease, and pancreatitis risk. High serum TG levels could be related to cardiovascular disease, which is the most prevalent cause of mortality in Western countries. The etiology of hypertriglyceridemia (HTG) is multifactorial and can be classified as primary and secondary causes. Among the primary causes are genetic disorders. On the other hand, secondary causes of HTG comprise lifestyle factors, medical conditions, and drugs. Among lifestyle changes, adequate diets and nutrition are the initial steps to treat and prevent serum lipid alterations. Dietary intervention for HTG is recommended in order to modify the amount of macronutrients. Macronutrient distribution changes such as fat or protein, low-carbohydrate diets, and caloric restriction seem to be effective strategies in reducing TG levels. Particularly, the Mediterranean diet is the dietary pattern with the most consistent evidence for efficacy in HTG while the use of omega-3 supplements consumption is the dietary component with the highest number of randomized clinical trials (RCT) carried out with effective results on reducing TG. The aim of this review was to provide a better comprehension between human nutrition and lipid metabolism.

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Section: Foodsmentioning

confidence: 99%

The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence

et al. 2022

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“…The lipidic characteristic of flaxseed, which is one of the best food sources of essential FAs, with a richness of phenolic and antioxidant compounds [ 90 , 91 ], makes this functional food an excellent daily dietary alternative. According to Kuang (2020) [ 92 ], the effect of biscuits with flaxseed meal supplement, consumed at approximately 100 g per day, is sufficient to obtain the metabolic benefits on body weight, BMI and TG for overweight and obese individuals.…”

Section: Current Status Of Knowledgementioning

confidence: 99%

Do Bioactive Food Compound with Avena sativa L., Linum usitatissimum L. and Glycine max L. Supplementation with Moringa oleifera Lam. Have a Role against Nutritional Disorders? An Overview of the In Vitro and In Vivo Evidence

et al. 2021

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Functional clinical nutrition is an integrative science; it uses dietary strategies, functional foods and medicinal plants, as well as combinations thereof. Both functional foods and medicinal plants, whether associated or not, form nutraceuticals, which can bring benefits to health, in addition to being included in the prevention and treatment of diseases. Some functional food effects from Avena sativa L (oats), Linum usitatissimum L. (brown flaxseed), Glycine max L. (soya) and Moringa oleifera have been proposed for nutritional disorders through in vitro and in vivo tests. A formulation called a bioactive food compound (BFC) showed efficiency in the association of oats, flaxseed and soy for dyslipidemia and obesity. In this review, we discuss the effects of BFCs in other nutritional disorders, as well as the beneficial effects of M. oleifera in obesity, cardiovascular disease, diabetes mellitus type 2, metabolic syndrome, intestinal inflammatory diseases/colorectal carcinogenesis and malnutrition. In addition, we hypothesized that a BFC enriched with M. oleifera could present a synergistic effect and play a potential benefit in nutritional disorders. The traditional consumption of M. oleifera preparations can allow associations with other formulations, such as BFCs. These nutraceutical formulations can be easily accepted and can be used in sweet preparations (fruit and/or vegetable juices, fruit and/or vegetable vitamins, porridges, yogurt, cream, mousses or fruit salads, cakes and cookies) or savory (vegetable purees, soups, broths and various sauces), cooked or not. These formulations can be low-cost and easy-to-use. The association of bioactive food substances in dietary formulations can facilitate adherence to consumption and, thus, contribute to the planning of future nutritional interventions for the prevention and adjuvant treatment of the clinical conditions presented in this study. This can be extended to the general population. However, an investigation through clinical studies is needed to prove applicability in humans.

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“…Em virtude da sua composição nutricional, a linhaça é estudada como uma possível aliada na redução de risco de doenças crônicas não transmissíveis (DCNT). São reportados na literatura vários benefícios associados ao seu consumo regular, entre eles efeitos hipocolesterolemiante (SAXENA & KATARE, 2014;KAWAKAMI et al, 2015;AKRAMI et al, 2018;PRASAD et al, 2020;HADI et al, 2020a), hipoglicemiante ZHU et al, 2020;KUANG et al, 2020), anti-hipertensivo (URSONIU et al, 2016 anticancerígeno (DE SILVA & ALCORN, 2019;PAL et al, 2019;TANNOUS et al, 2020), antioxidante (BIAO et al, 2020), redutor da inflamação (BASHIR et al, 2019;ASKARPOUR et al, 2020;PALLA et al, 2020 ) e laxativo (PARIKH et al, 2019).…”

Section: Composição Nutricionalunclassified

“…Ao final do estudo, houve queda de 10 mmHg na pressão sistólica e 7 mmHg na pressão diastólica, para o grupo que consumiu linhaça.KHALESI et al (2015) relataram um mínimo 12 semanas de consumo crônico da linhaça necessário para se obter alguma alteração na pressão arterial, e que a linhaça integral, moída seria mais benéfica em relação ao consumo do óleo ou das lignanas para controle da pressão arterial. IL-6 do grupo que ingeriu a farinha de linhaça foram significativamente menores do que o do grupo controle, evidenciando que os biscoitos suplementados com farinha de linhaça têm efeito benéfico em indivíduos com sobrepeso e obesidade(KUANG et al, 2020).Em um ensaio clínico controlado randomizado, 60 pacientes com síndrome metabólica receberam óleo de linhaça (25 mL/dia) durante 7 semanas. Após este período, observou-se que o consumo de óleo de linhaça melhorou os níveis de soro IL-6, mas não teve efeito sobre o estresse oxidativo e o escore de coagulação em pacientes com síndrome metabólica.…”

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Histórico, Usos E Importância Econômica Da Linhaça

Lúcio¹,

Follmann²,

Emanuelli³

et al. 2021

Linhaça: Perspectiva De Produção E Usos Na Alimentação Humana E Animal

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Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Defatted flaxseed flour improves weight loss and lipid profile in overweight and obese adults: a randomized controlled trial

Abstract: Scope Studies have suggested that food rich in dietary fiber may contribute to body weight loss, lower triacylglycerol (TG) levels. This study aimed to investigate the effect of flaxseed meal...

Cited by 14 publications

References 36 publications

The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence

The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence

Do Bioactive Food Compound with Avena sativa L., Linum usitatissimum L. and Glycine max L. Supplementation with Moringa oleifera Lam. Have a Role against Nutritional Disorders? An Overview of the In Vitro and In Vivo Evidence

Histórico, Usos E Importância Econômica Da Linhaça

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