DeepLocRNA: An Interpretable Deep Learning Model for Predicting RNA Subcellular Localization with domain-specific transfer-learning
Jun Wang,
Marc Horlacher,
Lixin Cheng
et al.
Abstract:Accurate prediction of RNA subcellular localization plays an important role in understanding cellular processes and functions. Although post-transcriptional processes are governed by trans-acting RNA-binding proteins (RBPs) through interaction with cis-regulatory RNA motifs, current methods do not incorporate RBP-binding information. In this paper, we propose DeepLocRNA, an interpretable deep-learning model that leverages a pre-trained multi-task RBP-binding prediction model to predict the subcellular localisa… Show more
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