Deeper-Layer Body Tissue Temperature Control Using Multi-sensory Transducer

Abstract

For the monitoring of deeper layers of human tissue temperature during cooling the four-thermistor transducer was proposed. The Steinhart-Hart equation was used to linearize the temperature-resistance characteristics of thermistors. Transducer structure and temperature fields in the tissues of the body were simulated using COMSOL Multiphysics. The ratio of transducer's equivalent thermal resistances was determined using numerical and physical experiments. The difference of values of the temperature measured at a depth of 30 mm in tissue by invasive and non-invasive method was less than ± 0.5°C.

Development of Body Tissue Temperature Control Transducer

“…As shown in [15], that this ratio must be more than four. So, the ratio of thermal resistors R1 and R2 of the thermal channels was chosen to be equal to five.…”

“…In [15] was shown, that muscle temperature can be measured using multi-sensory transducer. This time, we discuss new design of multi-sensory transducer, which structures are shown on Figure 1, because the thermal channel and isolation cover dimension, and the influence of channel material have not been clarified.…”

“…The temperature of transduser sensors 1, 2, 3, 4, 5 was measured using, as noted above, Fluke thermometer. The temperature on the boundary between plate surface and transduser pad can be calculated using the equation [15], modified as follows…”

“…So, the ratio of thermal resistors R1 and R2 of the thermal channels was chosen to be equal to five. To calculate the tissue temperature at a depth of 3 cm can be used the equation [15] T= 0.5026* Tss + 18.399,…”

Design and Optimization of Pulsed Magnetic Field Generator for Cell Magneto-Permeabilization

“…Taking into account the maximum current value of 938 A, that is supported by the proposed generator, we have designed an inductor that will allow generation of magnetic field in the range of 4 T-6 T. The structure of inductor and the resulting pulsed magnetic field amplitude have been simulated using finite element method analysis [19] in COMSOL Multiphysics (COMSOL, Sweden).…”