“…When accessing the vein, damage may occur to the thoracic duct, proximal arteries (ie, subclavian or carotid artery laceration), lung (pneumothorax), phrenic nerve, or endotracheal tube cuff. Significant complications due to the presence of the catheter in the endovascular space include arrhythmias (right bundle brunch block and complete heart block [3,4]), bacteremia, endocarditis [5], valvular damage [6], intracardiac knotting [7,8], catheter tip embolization [9], thrombosis with thromboembolism [10,11], atrial perforation [12], ventricular perforation [13], pulmonary infarction [2], air embolism [14], pulmonary artery perforation with hemorrhage [15,16], and death [2,14]. A case of a PAC-induced pulmonary artery rupture is presented along with a review of the literature.…”