Deep Venous Thrombosis and Pulmonary Embolism Caused by an Intravascular Synovial Sarcoma of the Common Femoral Vein

Abstract

Malignant tumors arising in deep veins of the lower extremities are very uncommon. To our best knowledge, this is the seventh case of a primary venous intravascular synovial sarcoma (SS) reported in literature. A 32-year-old woman was admitted with a second episode of deep venous thrombosis of the right lower limb and pulmonary embolism. Physical and radiological examinations showed besides the thrombosis a tumor arising from the right common femoral vein involving the bifurcation of the common femoral artery. At surgery, en block resection of the tumor including the deep femoral vein and arterial bifurcation was done with an arterial reconstruction using a synthetic graft. Histopathological examination revealed an intravascular SS of the common femoral vein. The mainstay of curative therapy is complete surgical resection of all tumor manifestations with negative histological margins.

Intravascular Synovial Sarcoma of the Pulmonary Artery with Massive Pleural Effusion: Report of a Case with a Favorable Response to Ifosfamide Chemotherapy and Palliative Radiation Therapy

“…In that study, among 13 patients who received ifosfamide chemotherapy, nine showed a partial response and four showed a complete response. Ifosfamide was also administered as adjuvant chemotherapy in all three previously reported patients with IVSS treated with surgical resection (7)(8)(9). In the present case of unresectable SS, the administration of ifosfamide chemotherapy plus palliative radiation therapy was effective.…”

Reasons why a second radiological opinion is advisable: a case report of a misreported crural synovial cell sarcoma

“…[20] 200841, maleRight superficial femoral veinBiphasicSchoneveld et al . [21] 201232, femaleRight common femoral veinMonophasicTuncer et al . [22] 201216, maleSuperior vena cava, right atriumBiphasicWise et al .…”